Biologically Active Small Molecules

A benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration causes non-depolarizing block of the neuromuscular junction.

A benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration causes non-depolarizing block of the neuromuscular junction.

A benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration causes non-depolarizing block of the neuromuscular junction.

A metabolite of atrazine.

An herbicide that is effective in controlling a broad range of weeds reportedly causes cancer in certain laboratory animals, has diverse effects on the reproductive system in animals and humans, and disrupts the normal function of the endocrine

Non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5 (pKBs range from 8.9-9.

Non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5 (pKBs range from 8.9-9.

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

A gold-thiol complex with anti-inflammatory and immunosuppressive actions potently inhibits thioredoxin reductase (IC₅₀ = 0.2 &muM) blocks LPS-mediated expression of inflammatory mediators at 10-20 &muM and blocks NF-&kappaB