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Biologically Active Small Molecules

  
  • azd 8330-1 mg
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    11588-1

    Thomas Scientific

    AZD 8330-1 mg

    Price: $149.40
    List Price: $166.00
    AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells.
    SKU11588-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0322-797
    Pack Size 1 EA
    Price:
    Price: $149.40
    List Price: $166.00
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  • azd 8330-10 mg
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    11588-10

    Thomas Scientific

    AZD 8330-10 mg

    Price: $511.24
    List Price: $568.04
    AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells.
    SKU11588-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0332-742
    Pack Size 1 EA
    Price:
    Price: $511.24
    List Price: $568.04
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  • azd 8330-5 mg
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    11588-5

    Thomas Scientific

    AZD 8330-5 mg

    Price: $367.32
    List Price: $408.14
    AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells.
    SKU11588-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0330-791
    Pack Size 1 EA
    Price:
    Price: $367.32
    List Price: $408.14
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  • azd 8330-50 mg
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    11588-50

    Thomas Scientific

    AZD 8330-50 mg

    Price: $1,768.93
    List Price: $1,965.48
    AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells.
    SKU11588-50
    MFR. NameCayman Chemical Company
    Catalog No. C08-0339-059
    Pack Size 1 EA
    Price:
    Price: $1,768.93
    List Price: $1,965.48
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    16237-1

    Thomas Scientific

    AZD 9291-1 mg

    Price: $77.11
    List Price: $85.68
    An irreversible inhibitor of EGFR sensitizing and T790M resistance mutations (IC<sub>50</sub>s = 15-17 nM) while sparing the wild-type EGFR (IC<sub>50</sub> = 480 nM) inhibits tumor growth in a xenograft mouse model at oral doses of 5-10 mg/kg.
    SKU16237-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0319-400
    Pack Size 1 EA
    Price:
    Price: $77.11
    List Price: $85.68
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    16237-10

    Thomas Scientific

    AZD 9291-10 mg

    Price: $307.05
    List Price: $341.17
    An irreversible inhibitor of EGFR sensitizing and T790M resistance mutations (IC<sub>50</sub>s = 15-17 nM) while sparing the wild-type EGFR (IC<sub>50</sub> = 480 nM) inhibits tumor growth in a xenograft mouse model at oral doses of 5-10 mg/kg.
    SKU16237-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0328-340
    Pack Size 1 EA
    Price:
    Price: $307.05
    List Price: $341.17
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    16237-5

    Thomas Scientific

    AZD 9291-5 mg

    Price: $189.98
    List Price: $211.09
    An irreversible inhibitor of EGFR sensitizing and T790M resistance mutations (IC<sub>50</sub>s = 15-17 nM) while sparing the wild-type EGFR (IC<sub>50</sub> = 480 nM) inhibits tumor growth in a xenograft mouse model at oral doses of 5-10 mg/kg.
    SKU16237-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0324-809
    Pack Size 1 EA
    Price:
    Price: $189.98
    List Price: $211.09
    Quantity:
     
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    16237-50

    Thomas Scientific

    AZD 9291-50 mg

    Price: $673.32
    List Price: $748.14
    An irreversible inhibitor of EGFR sensitizing and T790M resistance mutations (IC<sub>50</sub>s = 15-17 nM) while sparing the wild-type EGFR (IC<sub>50</sub> = 480 nM) inhibits tumor growth in a xenograft mouse model at oral doses of 5-10 mg/kg.
    SKU16237-50
    MFR. NameCayman Chemical Company
    Catalog No. C08-0335-241
    Pack Size 1 EA
    Price:
    Price: $673.32
    List Price: $748.14
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    10702-1

    Thomas Scientific

    AZD1480-1 mg

    Price: $100.31
    List Price: $111.46
    A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) displays good pharmacokinetics in vivo, inhibits STAT3 and STAT5 activation in vivo, and suppresses
    SKU10702-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0320-855
    Pack Size 1 EA
    Price:
    Price: $100.31
    List Price: $111.46
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  • azd1480-10 mg
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    10702-10

    Thomas Scientific

    AZD1480-10 mg

    Price: $415.38
    List Price: $461.53
    A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) displays good pharmacokinetics in vivo, inhibits STAT3 and STAT5 activation in vivo, and suppresses
    SKU10702-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0331-465
    Pack Size 1 EA
    Price:
    Price: $415.38
    List Price: $461.53
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  • azd1480-5 mg
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    10702-5

    Thomas Scientific

    AZD1480-5 mg

    Price: $288.28
    List Price: $320.31
    A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) displays good pharmacokinetics in vivo, inhibits STAT3 and STAT5 activation in vivo, and suppresses
    SKU10702-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0328-018
    Pack Size 1 EA
    Price:
    Price: $288.28
    List Price: $320.31
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  • azd1480-50 mg
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    10702-50

    Thomas Scientific

    AZD1480-50 mg

    Price: $1,332.04
    List Price: $1,480.05
    A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM) displays good pharmacokinetics in vivo, inhibits STAT3 and STAT5 activation in vivo, and suppresses
    SKU10702-50
    MFR. NameCayman Chemical Company
    Catalog No. C08-0338-415
    Pack Size 1 EA
    Price:
    Price: $1,332.04
    List Price: $1,480.05
    Quantity:
     
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