Biologically Active Small Molecules

A monobactam antibiotic that is effective against Gram-negative bacteria but inactive against Gram-positive bacteria.

A monobactam antibiotic that is effective against Gram-negative bacteria but inactive against Gram-positive bacteria.

A monobactam antibiotic that is effective against Gram-negative bacteria but inactive against Gram-positive bacteria.

A muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 &microM azumolene

A muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 &microM azumolene

A muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 &microM azumolene

An inhibitor of USP14 and UCHL5, two proteasome-associated deubiquitinases inhibits DUB activity in purified 19S proteasomes with an IC50 value of 2.1 &microM blocks tumor progression in vivo in mice and prevents organ infiltration in mouse

An inhibitor of USP14 and UCHL5, two proteasome-associated deubiquitinases inhibits DUB activity in purified 19S proteasomes with an IC50 value of 2.1 &microM blocks tumor progression in vivo in mice and prevents organ infiltration in mouse

An inhibitor of USP14 and UCHL5, two proteasome-associated deubiquitinases inhibits DUB activity in purified 19S proteasomes with an IC50 value of 2.1 &microM blocks tumor progression in vivo in mice and prevents organ infiltration in mouse

An inhibitor of USP14 and UCHL5, two proteasome-associated deubiquitinases inhibits DUB activity in purified 19S proteasomes with an IC50 value of 2.1 &microM blocks tumor progression in vivo in mice and prevents organ infiltration in mouse

A potent agonist of D₂receptors.

A potent agonist of D₂receptors.