Biologically Active Small Molecules

A flavonoid originally isolated from the roots of Scutellaria baicalensis Georg inhibits platelet 12-LO with an ID50 value of 0.12 &microM, with minimal inhibition of platelet COX-1 (IC₅₀ = 0.

A flavonoid originally isolated from the roots of Scutellaria baicalensis Georg inhibits platelet 12-LO with an ID50 value of 0.12 &microM, with minimal inhibition of platelet COX-1 (IC₅₀ = 0.

A flavonoid originally isolated from the roots of Scutellaria baicalensis Georg inhibits platelet 12-LO with an ID50 value of 0.12 &microM, with minimal inhibition of platelet COX-1 (IC₅₀ = 0.

A flavonoid originally isolated from the roots of Scutellaria baicalensis Georg inhibits platelet 12-LO with an ID50 value of 0.12 &microM, with minimal inhibition of platelet COX-1 (IC₅₀ = 0.

A natural meroterpene that has retinol-like effects on gene expression and properties of the skin has antioxidant and antibacterial actions inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 &microM).

A natural meroterpene that has retinol-like effects on gene expression and properties of the skin has antioxidant and antibacterial actions inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 &microM).

Balicatib is a potent inhibitor of cathepsin K (IC₅₀s = 1.4, 56, and 480 nM for human, rat, and mouse forms, respectively).

Balicatib is a potent inhibitor of cathepsin K (IC₅₀s = 1.4, 56, and 480 nM for human, rat, and mouse forms, respectively).

Balicatib is a potent inhibitor of cathepsin K (IC₅₀s = 1.4, 56, and 480 nM for human, rat, and mouse forms, respectively).

Balicatib is a potent inhibitor of cathepsin K (IC₅₀s = 1.4, 56, and 480 nM for human, rat, and mouse forms, respectively).

A prodrug for 5-ASA, which is effective against Crohn&rsquos disease and ulcerative colitis in animal models and clinical trials.

A prodrug for 5-ASA, which is effective against Crohn&rsquos disease and ulcerative colitis in animal models and clinical trials.