Biologically Active Small Molecules

A prodrug for 5-ASA, which is effective against Crohn&rsquos disease and ulcerative colitis in animal models and clinical trials.

A prodrug for 5-ASA, which is effective against Crohn&rsquos disease and ulcerative colitis in animal models and clinical trials.

BAM7 is a direct activator of Bax (EC₅₀ = 3.3 &microM) that engages the Bax trigger site and promotes the functional oligomerization of Bax.

BAM7 is a direct activator of Bax (EC₅₀ = 3.3 &microM) that engages the Bax trigger site and promotes the functional oligomerization of Bax.

BAM7 is a direct activator of Bax (EC₅₀ = 3.3 &microM) that engages the Bax trigger site and promotes the functional oligomerization of Bax.

BAM7 is a direct activator of Bax (EC₅₀ = 3.3 &microM) that engages the Bax trigger site and promotes the functional oligomerization of Bax.

Bovine adrenal medulla 12 peptide (BAM-12P) is a cleavage product of proenkephalin that binds &kappa-opioid receptors (&kappaORs). BAM-12P plays a role in antinociceptive signaling.

Bovine adrenal medulla 12 peptide (BAM-12P) is a cleavage product of proenkephalin that binds &kappa-opioid receptors (&kappaORs). BAM-12P plays a role in antinociceptive signaling.

Bovine adrenal medulla 12 peptide (BAM-12P) is a cleavage product of proenkephalin that binds &kappa-opioid receptors (&kappaORs). BAM-12P plays a role in antinociceptive signaling.

&kappaOR and &microOR agonist and cleavage product of proenkephalin.

&kappaOR and &microOR agonist and cleavage product of proenkephalin.

&kappaOR and &microOR agonist and cleavage product of proenkephalin.