Biologically Active Small Molecules

An inhibitor of LAT1 that blocks the uptake of L-leucine with an IC₅₀ value of 131.5 &microM and can inhibit all members of the LAT family at a concentration of 10 mM suppresses mTORC1 signaling that drives DNA synthesis and cell

Bambuterol is a long-acting ß2-adrenergic agonist and inhibitor of butylcholinesterase (BChE). Bambuterol is a prodrug of terbutaline and exhibits bronchodilatory and anti-asthma activities.

Bambuterol is a long-acting ß2-adrenergic agonist and inhibitor of butylcholinesterase (BChE). Bambuterol is a prodrug of terbutaline and exhibits bronchodilatory and anti-asthma activities.

Bambuterol is a long-acting ß2-adrenergic agonist and inhibitor of butylcholinesterase (BChE). Bambuterol is a prodrug of terbutaline and exhibits bronchodilatory and anti-asthma activities.

Bambuterol is a long-acting ß2-adrenergic agonist and inhibitor of butylcholinesterase (BChE). Bambuterol is a prodrug of terbutaline and exhibits bronchodilatory and anti-asthma activities.

A potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively.

A potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively.

A potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively.

A mycotoxin which is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 &muM induces apoptosis in mammalian cells with an IC50 value of 4.5 &muM.

A mycotoxin which is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 &muM induces apoptosis in mammalian cells with an IC50 value of 4.5 &muM.

A mycotoxin which is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 &muM induces apoptosis in mammalian cells with an IC50 value of 4.5 &muM.

L-Arginine serves as a common substrate for both NOS and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with N&omega-hydroxy-L-arginine (NOHA) formed as an intermediate.