Biologically Active Small Molecules

L-Arginine serves as a common substrate for both NOS and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with N&omega-hydroxy-L-arginine (NOHA) formed as an intermediate.

L-Arginine serves as a common substrate for both NOS and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with N&omega-hydroxy-L-arginine (NOHA) formed as an intermediate.

L-Arginine serves as a common substrate for both NOS and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with N&omega-hydroxy-L-arginine (NOHA) formed as an intermediate.

A water-soluble, diethylaminoethyl analog of the antineoplastic antibiotic rebeccamycin intercalates into DNA, stabilizing the DNA-topoisomerase complex, resulting in potent catalytic inhibition of both topoisomerases I and II, DNA cleavage and

A water-soluble, diethylaminoethyl analog of the antineoplastic antibiotic rebeccamycin intercalates into DNA, stabilizing the DNA-topoisomerase complex, resulting in potent catalytic inhibition of both topoisomerases I and II, DNA cleavage and

Apamin is a peptide bee venom toxin that acts as an antagonist at K+ channels. Apamin inhibits small- and intermediate-conductance Ca2+-activated K+ (SK2/3, IK) channels it blocks the pore region, preventing K+ ion transport and lowering the

Apamin is a peptide bee venom toxin that acts as an antagonist at K+ channels. Apamin inhibits small- and intermediate-conductance Ca2+-activated K+ (SK2/3, IK) channels it blocks the pore region, preventing K+ ion transport and lowering the

Apamin is a peptide bee venom toxin that acts as an antagonist at K+ channels. Apamin inhibits small- and intermediate-conductance Ca2+-activated K+ (SK2/3, IK) channels it blocks the pore region, preventing K+ ion transport and lowering the

HDAC inhibitor used to treat T cell lymphoma. It also induces apoptosis in pancreatic cancer cells and decreases HIV release from macrophages.

HDAC inhibitor used to treat T cell lymphoma. It also induces apoptosis in pancreatic cancer cells and decreases HIV release from macrophages.

Thiamine/vitamin B derivative and antioxidant. It displays several biological activities, including inhibiting pain neurotransmission, decreasing production of production of amyloid-&beta, and inhibiting LPS-induced release of leukotrienes,

Thiamine/vitamin B derivative and antioxidant. It displays several biological activities, including inhibiting pain neurotransmission, decreasing production of production of amyloid-&beta, and inhibiting LPS-induced release of leukotrienes,