Biologically Active Small Molecules

Betulin is a pentacyclic triterpene found in birch bark. This compound can induce apoptosis and inhibit angiogenesis, lending it a wide variety of functions, including anticancer, antiviral, anti-inflammatory, anti-fibrotic, antioxidative, and

A pentacyclic triperpene isolated from birch tree bark that inhibits the SREBP-driven pathway of cholesterol and fatty acid biosynthesis 15-30 mg/kg/day decreases lipid levels and increases insulin sensitivity in mice fed a western-type diet and

A pentacyclic triperpene isolated from birch tree bark that inhibits the SREBP-driven pathway of cholesterol and fatty acid biosynthesis 15-30 mg/kg/day decreases lipid levels and increases insulin sensitivity in mice fed a western-type diet and

A pentacyclic triperpene isolated from birch tree bark that inhibits the SREBP-driven pathway of cholesterol and fatty acid biosynthesis 15-30 mg/kg/day decreases lipid levels and increases insulin sensitivity in mice fed a western-type diet and

A pentacyclic triperpene isolated from birch tree bark that inhibits the SREBP-driven pathway of cholesterol and fatty acid biosynthesis 15-30 mg/kg/day decreases lipid levels and increases insulin sensitivity in mice fed a western-type diet and

Betulinic acid is a pentacyclic triterpene that exhibits antithrombotic, anti-atherosclerotic, antioxidative, anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic properties. Betulinic acid decreases expression of P-selectin and

Betulinic acid is a pentacyclic triterpene that exhibits antithrombotic, anti-atherosclerotic, antioxidative, anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic properties. Betulinic acid decreases expression of P-selectin and

Betulinic acid is a pentacyclic triterpene that exhibits antithrombotic, anti-atherosclerotic, antioxidative, anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic properties. Betulinic acid decreases expression of P-selectin and

An agonist of the bile acid receptor TGR5 (EC50 = 1 &microM) and blocks fatty liver development in cells and mice given ethanol reduces NF-&kappaB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1 inhibits

An agonist of the bile acid receptor TGR5 (EC50 = 1 &microM) and blocks fatty liver development in cells and mice given ethanol reduces NF-&kappaB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1 inhibits

An agonist of the bile acid receptor TGR5 (EC50 = 1 &microM) and blocks fatty liver development in cells and mice given ethanol reduces NF-&kappaB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1 inhibits

An agonist of the bile acid receptor TGR5 (EC50 = 1 &microM) and blocks fatty liver development in cells and mice given ethanol reduces NF-&kappaB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1 inhibits