Biologically Active Small Molecules

A stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives exhibits anti-oxidant and antimutagenic effects.

A yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions.

A yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions.

A yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions.

A green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and further reduced to bilirubin by biliverdin reductase possesses anti-mutagenic and antioxidant properties, scavenging free radicals.

A green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and further reduced to bilirubin by biliverdin reductase possesses anti-mutagenic and antioxidant properties, scavenging free radicals.

A green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and further reduced to bilirubin by biliverdin reductase possesses anti-mutagenic and antioxidant properties, scavenging free radicals.

A sesquiterpene lactone which protects against cerebral edema, decreases cortical infarct volume, and reduces cerebral ischemic damage at 10 &muM, reduces the release of glycine and glutamate from hippocampal slices under ischemic conditions

A sesquiterpene lactone which protects against cerebral edema, decreases cortical infarct volume, and reduces cerebral ischemic damage at 10 &muM, reduces the release of glycine and glutamate from hippocampal slices under ischemic conditions

An HNF4&alpha antagonist that can repress the expression of known HNF4&alpha target genes, inhibiting endogenous insulin expression in vitro (IC50 = 930 nM).

An HNF4&alpha antagonist that can repress the expression of known HNF4&alpha target genes, inhibiting endogenous insulin expression in vitro (IC50 = 930 nM).

An HNF4&alpha antagonist that can repress the expression of known HNF4&alpha target genes, inhibiting endogenous insulin expression in vitro (IC50 = 930 nM).