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12031-50An HNF4&alpha antagonist that can repress the expression of known HNF4&alpha target genes, inhibiting endogenous insulin expression in vitro (IC50 = 930 nM).
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11479-1An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 µM, respectively) and downregulates the NF-&kappaB pathway, preventing
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11479-10An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 µM, respectively) and downregulates the NF-&kappaB pathway, preventing
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11479-25An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 µM, respectively) and downregulates the NF-&kappaB pathway, preventing
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11479-5An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 µM, respectively) and downregulates the NF-&kappaB pathway, preventing
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A5130-100 mg
Thomas Scientific
Binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1 , TNF-a, BDNF, and GDNF and protects against prion-induced neurodegeneration. (C08-0488-513)
Price: $143.60List Price: $159.56Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1ß, TNF-a, -
A5130-250 mg
Thomas Scientific
Binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1 , TNF-a, BDNF, and GDNF and protects against prion-induced neurodegeneration. (C08-0488-657)
Price: $180.35List Price: $200.39Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1ß, TNF-a, -
A5130-500 mg
Thomas Scientific
Binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1 , TNF-a, BDNF, and GDNF and protects against prion-induced neurodegeneration. (C08-0488-778)
Price: $225.95List Price: $251.05Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1ß, TNF-a, -
A5130-1 g
Thomas Scientific
Binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1 , TNF-a, BDNF, and GDNF and protects against prion-induced neurodegeneration. (C08-0489-434)
Price: $556.51List Price: $618.35Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1ß, TNF-a, -
16996-10An orally bioavailable inhibitor of MEK1/2 (IC<sub>50</sub> = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC<sub>50</sub>s &ge 5 nM) efficacious in several xenograft tumor models in mice, including those bearing K-Ras or
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16996-100An orally bioavailable inhibitor of MEK1/2 (IC<sub>50</sub> = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC<sub>50</sub>s &ge 5 nM) efficacious in several xenograft tumor models in mice, including those bearing K-Ras or
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16996-5An orally bioavailable inhibitor of MEK1/2 (IC<sub>50</sub> = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC<sub>50</sub>s &ge 5 nM) efficacious in several xenograft tumor models in mice, including those bearing K-Ras or