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Biologically Active Small Molecules

  
  • bim5078-50 mg
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    12031-50

    Thomas Scientific

    BIM5078-50 mg

    Price: $842.97
    List Price: $936.64
    An HNF4&alpha antagonist that can repress the expression of known HNF4&alpha target genes, inhibiting endogenous insulin expression in vitro (IC50 = 930 nM).
    SKU12031-50
    MFR. NameCayman Chemical Company
    Catalog No. C08-0336-665
    Pack Size 1 EA
    Price:
    Price: $842.97
    List Price: $936.64
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    11479-1

    Thomas Scientific

    Bindarit-1 mg

    Price: $60.25
    List Price: $66.94
    An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 &microM, respectively) and downregulates the NF-&kappaB pathway, preventing
    SKU11479-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0318-871
    Pack Size 1 EA
    Price:
    Price: $60.25
    List Price: $66.94
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  • bindarit-10 mg
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    11479-10

    Thomas Scientific

    Bindarit-10 mg

    Price: $284.02
    List Price: $315.58
    An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 &microM, respectively) and downregulates the NF-&kappaB pathway, preventing
    SKU11479-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0328-851
    Pack Size 1 EA
    Price:
    Price: $284.02
    List Price: $315.58
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  • bindarit-25 mg
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    11479-25

    Thomas Scientific

    Bindarit-25 mg

    Price: $473.37
    List Price: $525.96
    An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 &microM, respectively) and downregulates the NF-&kappaB pathway, preventing
    SKU11479-25
    MFR. NameCayman Chemical Company
    Catalog No. C08-0332-307
    Pack Size 1 EA
    Price:
    Price: $473.37
    List Price: $525.96
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  • bindarit-5 mg
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    11479-5

    Thomas Scientific

    Bindarit-5 mg

    Price: $194.40
    List Price: $216.00
    An inhibitor of the expression of CCL2, CCL7, and CCL8, as well as IL-12 prevents LPS or C. albicans-induced production of CCL2 in human monocytes (IC50s = 172 and 403 &microM, respectively) and downregulates the NF-&kappaB pathway, preventing
    SKU11479-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0325-303
    Pack Size 1 EA
    Price:
    Price: $194.40
    List Price: $216.00
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  • binds ergosterol and induces membrane pore formations, incre (c08-0488-513)
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    A5130-100 mg
    Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1&szlig, TNF-a,
    SKUA5130-100 mg
    MFR. NameLKT Laboratories, Inc
    Catalog No. C08-0488-513
    Pack Size 1 EA
    Price:
    Price: $143.60
    List Price: $159.56
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  • binds ergosterol and induces membrane pore formations, incre (c08-0488-657)
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    A5130-250 mg
    Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1&szlig, TNF-a,
    SKUA5130-250 mg
    MFR. NameLKT Laboratories, Inc
    Catalog No. C08-0488-657
    Pack Size 1 EA
    Price:
    Price: $180.35
    List Price: $200.39
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  • binds ergosterol and induces membrane pore formations, incre (c08-0488-778)
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    A5130-500 mg
    Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1&szlig, TNF-a,
    SKUA5130-500 mg
    MFR. NameLKT Laboratories, Inc
    Catalog No. C08-0488-778
    Pack Size 1 EA
    Price:
    Price: $225.95
    List Price: $251.05
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  • binds ergosterol and induces membrane pore formations, incre (c08-0489-434)
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    A5130-1 g
    Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1&szlig, TNF-a,
    SKUA5130-1 g
    MFR. NameLKT Laboratories, Inc
    Catalog No. C08-0489-434
    Pack Size 1 EA
    Price:
    Price: $556.51
    List Price: $618.35
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    16996-10

    Thomas Scientific

    Binimetinib-10 mg

    Price: $236.37
    List Price: $262.63
    An orally bioavailable inhibitor of MEK1/2 (IC<sub>50</sub> = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC<sub>50</sub>s &ge 5 nM) efficacious in several xenograft tumor models in mice, including those bearing K-Ras or
    SKU16996-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0326-587
    Pack Size 1 EA
    Price:
    Price: $236.37
    List Price: $262.63
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    16996-100

    Thomas Scientific

    Binimetinib-100 mg

    Price: $1,351.94
    List Price: $1,502.16
    An orally bioavailable inhibitor of MEK1/2 (IC<sub>50</sub> = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC<sub>50</sub>s &ge 5 nM) efficacious in several xenograft tumor models in mice, including those bearing K-Ras or
    SKU16996-100
    MFR. NameCayman Chemical Company
    Catalog No. C08-0338-456
    Pack Size 1 EA
    Price:
    Price: $1,351.94
    List Price: $1,502.16
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    16996-5

    Thomas Scientific

    Binimetinib-5 mg

    Price: $137.36
    List Price: $152.62
    An orally bioavailable inhibitor of MEK1/2 (IC<sub>50</sub> = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC<sub>50</sub>s &ge 5 nM) efficacious in several xenograft tumor models in mice, including those bearing K-Ras or
    SKU16996-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0322-165
    Pack Size 1 EA
    Price:
    Price: $137.36
    List Price: $152.62
    Quantity:
     
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