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Add to Cart The item has been added16996-50An orally bioavailable inhibitor of MEK1/2 (IC<sub>50</sub> = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC<sub>50</sub>s &ge 5 nM) efficacious in several xenograft tumor models in mice, including those bearing K-Ras or -
Add to Cart The item has been added13123-1A cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3&alpha/&beta (IC<sub>50</sub> = 5 nM) inhibition of GSK activates the Wnt-signaling pathway and sustains
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Add to Cart The item has been added13123-10A cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3&alpha/&beta (IC<sub>50</sub> = 5 nM) inhibition of GSK activates the Wnt-signaling pathway and sustains -
Add to Cart The item has been added13123-25A cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3&alpha/&beta (IC<sub>50</sub> = 5 nM) inhibition of GSK activates the Wnt-signaling pathway and sustains -
Add to Cart The item has been added13123-5A cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3&alpha/&beta (IC<sub>50</sub> = 5 nM) inhibition of GSK activates the Wnt-signaling pathway and sustains -
Add to Cart The item has been added16329-1A potent inhibitor of GSK3&alpha/&beta (IC<sub>50</sub> = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC<sub>50</sub>s = 2.4, 4.
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Add to Cart The item has been added16329-10A potent inhibitor of GSK3&alpha/&beta (IC<sub>50</sub> = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC<sub>50</sub>s = 2.4, 4.
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Add to Cart The item has been added16329-5A potent inhibitor of GSK3&alpha/&beta (IC<sub>50</sub> = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC<sub>50</sub>s = 2.4, 4.
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Add to Cart The item has been added16476-1A phytoestrogen that can affect hormone levels by inhibiting 5&alpha-reductase and 17&beta-hydroxysteroid dehydrogenase or altering aromatase (CYP19A1) activity activates PPAR&gamma (IC<sub>50</sub> = 19 µM) and increases the expression of
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Add to Cart The item has been added16476-100A phytoestrogen that can affect hormone levels by inhibiting 5&alpha-reductase and 17&beta-hydroxysteroid dehydrogenase or altering aromatase (CYP19A1) activity activates PPAR&gamma (IC<sub>50</sub> = 19 µM) and increases the expression of
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Add to Cart The item has been added16476-250A phytoestrogen that can affect hormone levels by inhibiting 5&alpha-reductase and 17&beta-hydroxysteroid dehydrogenase or altering aromatase (CYP19A1) activity activates PPAR&gamma (IC<sub>50</sub> = 19 µM) and increases the expression of
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Add to Cart The item has been added16751-10A conjugate of biotin and lysine used for derivatization or conjugation to proteins and other molecules with a medium-chain length spacer also used as an anterograde, retrograde, or intracellular neuroanatomical tracer that is fixable with
