Biologically Active Small Molecules

An antagonist of cIAP1, cIAP2, and XIAP.

An antagonist of cIAP1, cIAP2, and XIAP.

An antagonist of cIAP1, cIAP2, and XIAP.

A tacrine dimer, linked via a 7-carbon alkyl spacer inhibits AChE (IC50 = 0.40 nM), making it more than 1,000 times more potent than tacrine protects against hydrogen peroxide induced apoptosis in rat pheochromocytoma cells.

A tacrine dimer, linked via a 7-carbon alkyl spacer inhibits AChE (IC50 = 0.40 nM), making it more than 1,000 times more potent than tacrine protects against hydrogen peroxide induced apoptosis in rat pheochromocytoma cells.

A tacrine dimer, linked via a 7-carbon alkyl spacer inhibits AChE (IC50 = 0.40 nM), making it more than 1,000 times more potent than tacrine protects against hydrogen peroxide induced apoptosis in rat pheochromocytoma cells.

A tacrine dimer, linked via a 7-carbon alkyl spacer inhibits AChE (IC50 = 0.40 nM), making it more than 1,000 times more potent than tacrine protects against hydrogen peroxide induced apoptosis in rat pheochromocytoma cells.

An inhibitor of FAS-II, blocking fatty acid synthesis in S. aureus and E.

An inhibitor of FAS-II, blocking fatty acid synthesis in S. aureus and E.

A natural demethoxy derivative of curcumin activates macrophage phagocytosis and, with 1&alpha,25-dihydroxyvitamin D3, stimulates amyloid-&beta clearance by macrophages (optimal stimulation at 100 nM BDMC) suppresses proliferation in cancer

A natural demethoxy derivative of curcumin activates macrophage phagocytosis and, with 1&alpha,25-dihydroxyvitamin D3, stimulates amyloid-&beta clearance by macrophages (optimal stimulation at 100 nM BDMC) suppresses proliferation in cancer

A natural demethoxy derivative of curcumin activates macrophage phagocytosis and, with 1&alpha,25-dihydroxyvitamin D3, stimulates amyloid-&beta clearance by macrophages (optimal stimulation at 100 nM BDMC) suppresses proliferation in cancer