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Biologically Active Small Molecules

  
  • bisindolylmaleimide iv-5 mg
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    13299-5

    Thomas Scientific

    Bisindolylmaleimide IV-5 mg

    Price: $429.82
    List Price: $477.58
    A cell permeable inhibitor of PKC with IC<sub>50</sub> values reported to range from 0.10 to 0.
    SKU13299-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0331-646
    Pack Size 1 EA
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    Price: $429.82
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  • bisindolylmaleimide ix (mesylate)-1 mg
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    13334-1

    Thomas Scientific

    Bisindolylmaleimide IX (mesylate)-1 mg

    Price: $106.02
    List Price: $117.80
    A potent, cell-permeable inhibitor of PKC isoforms (IC<sub>50</sub> = 5, 24, 14, 27, and 24 nM for PKC-&alpha, PKC-&betaI, PKC-&betaII, PKC-&gamma, and PKC-&epsilon, respectively).
    SKU13334-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0321-355
    Pack Size 1 EA
    Price:
    Price: $106.02
    List Price: $117.80
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  • bisindolylmaleimide ix (mesylate)-10 mg
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    13334-10

    Thomas Scientific

    Bisindolylmaleimide IX (mesylate)-10 mg

    Price: $458.21
    List Price: $509.12
    A potent, cell-permeable inhibitor of PKC isoforms (IC<sub>50</sub> = 5, 24, 14, 27, and 24 nM for PKC-&alpha, PKC-&betaI, PKC-&betaII, PKC-&gamma, and PKC-&epsilon, respectively).
    SKU13334-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0332-159
    Pack Size 1 EA
    Price:
    Price: $458.21
    List Price: $509.12
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  • bisindolylmaleimide ix (mesylate)-5 mg
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    13334-5

    Thomas Scientific

    Bisindolylmaleimide IX (mesylate)-5 mg

    Price: $314.31
    List Price: $349.24
    A potent, cell-permeable inhibitor of PKC isoforms (IC<sub>50</sub> = 5, 24, 14, 27, and 24 nM for PKC-&alpha, PKC-&betaI, PKC-&betaII, PKC-&gamma, and PKC-&epsilon, respectively).
    SKU13334-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0329-679
    Pack Size 1 EA
    Price:
    Price: $314.31
    List Price: $349.24
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  • bisindolylmaleimide v-1 mg
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    13300-1

    Thomas Scientific

    Bisindolylmaleimide V-1 mg

    Price: $154.23
    List Price: $171.36
    A weak inhibitor of PKC demonstrating an IC<sub>50</sub> value &gt100 &microM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC<sub>50</sub> value of 8 &microM.
    SKU13300-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0323-309
    Pack Size 1 EA
    Price:
    Price: $154.23
    List Price: $171.36
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  • bisindolylmaleimide v-10 mg
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    13300-10

    Thomas Scientific

    Bisindolylmaleimide V-10 mg

    Price: $878.32
    List Price: $975.91
    A weak inhibitor of PKC demonstrating an IC<sub>50</sub> value &gt100 &microM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC<sub>50</sub> value of 8 &microM.
    SKU13300-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0336-923
    Pack Size 1 EA
    Price:
    Price: $878.32
    List Price: $975.91
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  • bisindolylmaleimide v-25 mg
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    13300-25

    Thomas Scientific

    Bisindolylmaleimide V-25 mg

    Price: $1,842.00
    List Price: $2,046.67
    A weak inhibitor of PKC demonstrating an IC<sub>50</sub> value &gt100 &microM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC<sub>50</sub> value of 8 &microM.
    SKU13300-25
    MFR. NameCayman Chemical Company
    Catalog No. C08-0339-133
    Pack Size 1 EA
    Price:
    Price: $1,842.00
    List Price: $2,046.67
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  • bisindolylmaleimide v-5 mg
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    13300-5

    Thomas Scientific

    Bisindolylmaleimide V-5 mg

    Price: $530.17
    List Price: $589.07
    A weak inhibitor of PKC demonstrating an IC<sub>50</sub> value &gt100 &microM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC<sub>50</sub> value of 8 &microM.
    SKU13300-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0333-084
    Pack Size 1 EA
    Price:
    Price: $530.17
    List Price: $589.07
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  • bisindolylmaleimide viii (acetate)-1 mg
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    13333-1

    Thomas Scientific

    Bisindolylmaleimide VIII (acetate)-1 mg

    Price: $120.49
    List Price: $133.88
    A selective PKC inhibitor (IC<sub>50</sub> = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC exhibits PKC isozyme specificity with preference for PKC&alpha over PKC&betaI, PKC&betaII, PKC&gamma, or PKC&epsilon
    SKU13333-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0321-720
    Pack Size 1 EA
    Price:
    Price: $120.49
    List Price: $133.88
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  • bisindolylmaleimide viii (acetate)-10 mg
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    13333-10

    Thomas Scientific

    Bisindolylmaleimide VIII (acetate)-10 mg

    Price: $602.63
    List Price: $669.58
    A selective PKC inhibitor (IC<sub>50</sub> = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC exhibits PKC isozyme specificity with preference for PKC&alpha over PKC&betaI, PKC&betaII, PKC&gamma, or PKC&epsilon
    SKU13333-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0334-517
    Pack Size 1 EA
    Price:
    Price: $602.63
    List Price: $669.58
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  • bisindolylmaleimide viii (acetate)-5 mg
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    13333-5

    Thomas Scientific

    Bisindolylmaleimide VIII (acetate)-5 mg

    Price: $346.52
    List Price: $385.02
    A selective PKC inhibitor (IC<sub>50</sub> = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC exhibits PKC isozyme specificity with preference for PKC&alpha over PKC&betaI, PKC&betaII, PKC&gamma, or PKC&epsilon
    SKU13333-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0330-258
    Pack Size 1 EA
    Price:
    Price: $346.52
    List Price: $385.02
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    17511-1

    Thomas Scientific

    Bisindolylmaleimide X (hydrochloride)-1 mg

    Price: $153.63
    List Price: $170.71
    A cell-permeable, reversible, ATP-competitive PKC inhibitor (IC<sub>50</sub> = 15 nM, rat brain PKC) inhibits PKC&alpha, &betaI, &betaII, &gamma, and &epsilon with IC<sub>50</sub> values of 8, 8, 14, 13, and 39 nM, respectively also inhibits
    SKU17511-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0323-096
    Pack Size 1 EA
    Price:
    Price: $153.63
    List Price: $170.71
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