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16667-10A selective, cell permeable inhibitor of the I&kappaB kinases IKK&alpha and IKK&beta (IC<sub>50</sub>s = 4 and 0.3 µM) inhibits signaling through NF-&kappaB both in cells and in vivo, showing excellent pharmacokinetics in mice.
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16667-25A selective, cell permeable inhibitor of the I&kappaB kinases IKK&alpha and IKK&beta (IC<sub>50</sub>s = 4 and 0.3 µM) inhibits signaling through NF-&kappaB both in cells and in vivo, showing excellent pharmacokinetics in mice.
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16667-5A selective, cell permeable inhibitor of the I&kappaB kinases IKK&alpha and IKK&beta (IC<sub>50</sub>s = 4 and 0.3 µM) inhibits signaling through NF-&kappaB both in cells and in vivo, showing excellent pharmacokinetics in mice.
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19076-1A RAR&beta agonist, RAR&alpha/&gamma antagonist that inhibit the proliferation of normal breast cells via the induction of TGF-&beta activity, causing G1 arrest used to trigger the differentiation of mouse embryonic stem cells.
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19076-10A RAR&beta agonist, RAR&alpha/&gamma antagonist that inhibit the proliferation of normal breast cells via the induction of TGF-&beta activity, causing G1 arrest used to trigger the differentiation of mouse embryonic stem cells.
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19076-25A RAR&beta agonist, RAR&alpha/&gamma antagonist that inhibit the proliferation of normal breast cells via the induction of TGF-&beta activity, causing G1 arrest used to trigger the differentiation of mouse embryonic stem cells.
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19076-5A RAR&beta agonist, RAR&alpha/&gamma antagonist that inhibit the proliferation of normal breast cells via the induction of TGF-&beta activity, causing G1 arrest used to trigger the differentiation of mouse embryonic stem cells.
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17418-1A pan-RAR inverse agonist that blocks RAR&alpha activity with an IC<sub>50</sub> value of 114 nM prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions.
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17418-10A pan-RAR inverse agonist that blocks RAR&alpha activity with an IC<sub>50</sub> value of 114 nM prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions.
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17418-25A pan-RAR inverse agonist that blocks RAR&alpha activity with an IC<sub>50</sub> value of 114 nM prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions.
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17418-5A pan-RAR inverse agonist that blocks RAR&alpha activity with an IC<sub>50</sub> value of 114 nM prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions.
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18413-1CAS Number: 701213-36-7 Synonyms: Temsavir Molecular Formula: C<sub>24</sub>H<sub>23</sub>N<sub>7</sub>O<sub>4</sub> Formula Weight: 473.5