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Biologically Active Small Molecules

  
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    14433-5

    Thomas Scientific

    bpV(HOpic) (potassium salt)-5 mg

    Price: $171.35
    List Price: $190.39
    A bpV compound that selectively inhibits PTEN (IC<sub>50</sub> = 14 nM) also inhibits the vascular endothelial PTP, PTP-&beta (IC<sub>50</sub> = 4.9 &muM), and PTP-1&betaB (IC<sub>50</sub> = 25.3 &muM) with reduced potency.
    SKU14433-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0326-693
    Pack Size 1 EA
    Price:
    Price: $171.35
    List Price: $190.39
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    15438-25

    Thomas Scientific

    bpV(HOpic) (potassium salt, technical grade)-25 mg

    Price: $359.77
    List Price: $399.74
    A bisperoxovanadium compound that selectively inhibits PTEN (IC<sub>50</sub> = 14 nM) also inhibits the vascular endothelial protein tyrosine phosphatase, PTP-&beta (IC<sub>50</sub> = 4.9 &muM), and PTP-1&betaB (IC<sub>50</sub> = 25.
    SKU15438-25
    MFR. NameCayman Chemical Company
    Catalog No. C08-0330-545
    Pack Size 1 EA
    Price:
    Price: $359.77
    List Price: $399.74
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    15438-5

    Thomas Scientific

    bpV(HOpic) (potassium salt, technical grade)-5 mg

    Price: $106.02
    List Price: $117.80
    A bisperoxovanadium compound that selectively inhibits PTEN (IC<sub>50</sub> = 14 nM) also inhibits the vascular endothelial protein tyrosine phosphatase, PTP-&beta (IC<sub>50</sub> = 4.9 &muM), and PTP-1&betaB (IC<sub>50</sub> = 25.
    SKU15438-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0321-311
    Pack Size 1 EA
    Price:
    Price: $106.02
    List Price: $117.80
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  • bpv(phen) (potassium hydrate)-25 mg
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    13331-25

    Thomas Scientific

    bpV(phen) (potassium hydrate)-25 mg

    Price: $372.18
    List Price: $413.54
    An inhibitor of several different PTPs, with selectivity for PTEN (IC<sub>50</sub> = 38 nM) also inhibits PTP-&beta (IC<sub>50</sub> = 343 nM), PTP-1&beta (IC<sub>50</sub> = 920 nM), and SHIP-2 activates the insulin receptor tyrosine kinase and
    SKU13331-25
    MFR. NameCayman Chemical Company
    Catalog No. C08-0330-828
    Pack Size 1 EA
    Price:
    Price: $372.18
    List Price: $413.54
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    13331-5

    Thomas Scientific

    bpV(phen) (potassium hydrate)-5 mg

    Price: $99.87
    List Price: $110.96
    An inhibitor of several different PTPs, with selectivity for PTEN (IC<sub>50</sub> = 38 nM) also inhibits PTP-&beta (IC<sub>50</sub> = 343 nM), PTP-1&beta (IC<sub>50</sub> = 920 nM), and SHIP-2 activates the insulin receptor tyrosine kinase and
    SKU13331-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0320-863
    Pack Size 1 EA
    Price:
    Price: $99.87
    List Price: $110.96
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    14434-25

    Thomas Scientific

    bpV(pic) (potassium hydrate)-25 mg

    Price: $619.64
    List Price: $688.49
    A bpV compound that selectivity inhibits PTEN (IC<sub>50</sub> = 31 nM) also inhibits the vascular endothelial PTP, PTP-&beta (IC<sub>50</sub> = 12.7 &muM), and PTP-1&betaB (IC<sub>50</sub> = 61 &muM) and is known to be an insulin mimetic
    SKU14434-25
    MFR. NameCayman Chemical Company
    Catalog No. C08-0334-758
    Pack Size 1 EA
    Price:
    Price: $619.64
    List Price: $688.49
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    14434-5

    Thomas Scientific

    bpV(pic) (potassium hydrate)-5 mg

    Price: $183.07
    List Price: $203.41
    A bpV compound that selectivity inhibits PTEN (IC<sub>50</sub> = 31 nM) also inhibits the vascular endothelial PTP, PTP-&beta (IC<sub>50</sub> = 12.7 &muM), and PTP-1&betaB (IC<sub>50</sub> = 61 &muM) and is known to be an insulin mimetic
    SKU14434-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0324-683
    Pack Size 1 EA
    Price:
    Price: $183.07
    List Price: $203.41
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    17403-1

    Thomas Scientific

    BQ-788 (sodium salt)-1 mg

    Price: $458.21
    List Price: $509.12
    A potent, selective antagonist of ETB (IC<sub>50</sub> = 1.2 nM for blocking ET-1 binding to human Girardi heart cells) competitively antagonizes the vasoconstriction induced by an ETB-selective agonist on isolated rabbit pulmonary arteries.
    SKU17403-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0332-058
    Pack Size 1 EA
    Price:
    Price: $458.21
    List Price: $509.12
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    17403-500

    Thomas Scientific

    BQ-788 (sodium salt)-500 æg

    Price: $331.36
    List Price: $368.17
    A potent, selective antagonist of ETB (IC<sub>50</sub> = 1.2 nM for blocking ET-1 binding to human Girardi heart cells) competitively antagonizes the vasoconstriction induced by an ETB-selective agonist on isolated rabbit pulmonary arteries.
    SKU17403-500
    MFR. NameCayman Chemical Company
    Catalog No. C08-0330-001
    Pack Size 1 EA
    Price:
    Price: $331.36
    List Price: $368.17
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    15393-10

    Thomas Scientific

    BQCA-10 mg

    Price: $212.06
    List Price: $235.62
    A positive allosteric modulator of the M1 mAChR dose-dependently reduces the concentration of acetylcholine required to activate M1 the effective range for potentiation is 0.1 to 100 &muM with 3 nM acetylcholine restores impairment in reversal
    SKU15393-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0325-912
    Pack Size 1 EA
    Price:
    Price: $212.06
    List Price: $235.62
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    15393-25

    Thomas Scientific

    BQCA-25 mg

    Price: $426.03
    List Price: $473.37
    A positive allosteric modulator of the M1 mAChR dose-dependently reduces the concentration of acetylcholine required to activate M1 the effective range for potentiation is 0.1 to 100 &muM with 3 nM acetylcholine restores impairment in reversal
    SKU15393-25
    MFR. NameCayman Chemical Company
    Catalog No. C08-0331-609
    Pack Size 1 EA
    Price:
    Price: $426.03
    List Price: $473.37
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    15393-5

    Thomas Scientific

    BQCA-5 mg

    Price: $149.40
    List Price: $166.00
    A positive allosteric modulator of the M1 mAChR dose-dependently reduces the concentration of acetylcholine required to activate M1 the effective range for potentiation is 0.1 to 100 &muM with 3 nM acetylcholine restores impairment in reversal
    SKU15393-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0322-742
    Pack Size 1 EA
    Price:
    Price: $149.40
    List Price: $166.00
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