Biologically Active Small Molecules

A loop diuretic with good absorption and pharmacodynamic properties acts as an inhibitor of NKCC1 and the kidney-specific NKCC2 (Ki = 0.5 and 59 &muM for human and rabbit NKCC1, respectively).

A loop diuretic with good absorption and pharmacodynamic properties acts as an inhibitor of NKCC1 and the kidney-specific NKCC2 (Ki = 0.5 and 59 &muM for human and rabbit NKCC1, respectively).

A loop diuretic with good absorption and pharmacodynamic properties acts as an inhibitor of NKCC1 and the kidney-specific NKCC2 (Ki = 0.5 and 59 &muM for human and rabbit NKCC1, respectively).

A loop diuretic with good absorption and pharmacodynamic properties acts as an inhibitor of NKCC1 and the kidney-specific NKCC2 (Ki = 0.5 and 59 &muM for human and rabbit NKCC1, respectively).

An amino-amide anesthetic that binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, preventing the generation of an action potential inhibits the uptake of dopamine in striatal synaptosomes

An amino-amide anesthetic that binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, preventing the generation of an action potential inhibits the uptake of dopamine in striatal synaptosomes

An amino-amide anesthetic that binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, preventing the generation of an action potential inhibits the uptake of dopamine in striatal synaptosomes

An amino-amide anesthetic that binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, preventing the generation of an action potential inhibits the uptake of dopamine in striatal synaptosomes

CAS Number: 474668-57-0 Molecular Formula: C₁₈H₁₉D₉N₂O Formula Weight: 297.5

CAS Number: 474668-57-0 Molecular Formula: C₁₈H₁₉D₉N₂O Formula Weight: 297.5

CAS Number: 474668-57-0 Molecular Formula: C₁₈H₁₉D₉N₂O Formula Weight: 297.5

An alkyl sulfonate that acts as an alkylating antineoplastic agent forms both intra- and interstrand crosslinks on DNA, in addition to monoalkylation, primarily at guanine-N7, of DNA.