Biologically Active Small Molecules

A PAF analog.

A PAF analog.

An irreversible inhibitor of &gamma-glutamylcysteine synthetase (Ki limiting enzyme for GSH synthesis, that induces oxidative stress in cells by depleting GSH enhances the toxicity of various chemotherapeutic agents in drug-resistant tumors.

An irreversible inhibitor of &gamma-glutamylcysteine synthetase (Ki limiting enzyme for GSH synthesis, that induces oxidative stress in cells by depleting GSH enhances the toxicity of various chemotherapeutic agents in drug-resistant tumors.

An irreversible inhibitor of &gamma-glutamylcysteine synthetase (Ki limiting enzyme for GSH synthesis, that induces oxidative stress in cells by depleting GSH enhances the toxicity of various chemotherapeutic agents in drug-resistant tumors.

Specifically inhibits the histone acetyltransferase Gcn5 (IC₅₀ = 100 &muM) and can inhibit pre-RNA splicing with an IC₅₀ value of 0.5 mM.

Specifically inhibits the histone acetyltransferase Gcn5 (IC₅₀ = 100 &muM) and can inhibit pre-RNA splicing with an IC₅₀ value of 0.5 mM.

A cell-permeable inhibitor of PTPs (IC₅₀s = 0.09-1.

A cell-permeable inhibitor of PTPs (IC₅₀s = 0.09-1.

A cell-permeable inhibitor of PTPs (IC₅₀s = 0.09-1.

A cell-permeable inhibitor of PTPs (IC₅₀s = 0.09-1.

BW 245C is a selective agonist for the DP1 receptor. The Ki of BW 245C for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.