Biologically Active Small Molecules

An endogenous ceramide, generated by ceramide synthase 6, that acts a lipid second messenger to regulate apoptosis and stress signaling.

C-2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides.

C-2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides.

C-2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides.

C-2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides.

A natural 20:0 ceramide that is abundant in the brain synthesized de novo by ceramide synthases 1 and 2.

A natural 20:0 ceramide that is abundant in the brain synthesized de novo by ceramide synthases 1 and 2.

A natural 20:0 ceramide that is abundant in the brain synthesized de novo by ceramide synthases 1 and 2.

A natural 20:0 ceramide that is abundant in the brain synthesized de novo by ceramide synthases 1 and 2.

C-6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C-2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides.

C-6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C-2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides.

C-6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C-2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides.