Biologically Active Small Molecules

C-8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C-8 ceramide-1-phosphate are essentially the opposite of C-8 ceramide it induces DNA synthesis and cell division.

C-8 ceramide-1-phosphate is a short-chain analog of the naturally occurring ceramide-1-phosphate. The effects of C-8 ceramide-1-phosphate are essentially the opposite of C-8 ceramide it induces DNA synthesis and cell division.

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels.

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels.

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels.

C-8 ceramine is an analog of C-8 ceramide in which the carbonyl group of the ceramide is replaced by a methylene group. At a concentration of 10 &microM, C-8 ceramine induces maximal DNA fragmentation in U937 cells after 6 hours of incubation,

C-8 ceramine is an analog of C-8 ceramide in which the carbonyl group of the ceramide is replaced by a methylene group. At a concentration of 10 &microM, C-8 ceramine induces maximal DNA fragmentation in U937 cells after 6 hours of incubation,

C-8 ceramine is an analog of C-8 ceramide in which the carbonyl group of the ceramide is replaced by a methylene group. At a concentration of 10 &microM, C-8 ceramine induces maximal DNA fragmentation in U937 cells after 6 hours of incubation,

An inhibitor of the HAT p300 (IC50 = 1.6 &muM) competitively binds p300 (Ki = 400 nM) and does not inhibit several other acetyltransferases blocks the growth of human melanoma, leukemia, lung, and prostate cancer cells in vitro.

An inhibitor of the HAT p300 (IC50 = 1.6 &muM) competitively binds p300 (Ki = 400 nM) and does not inhibit several other acetyltransferases blocks the growth of human melanoma, leukemia, lung, and prostate cancer cells in vitro.

An inhibitor of the HAT p300 (IC50 = 1.6 &muM) competitively binds p300 (Ki = 400 nM) and does not inhibit several other acetyltransferases blocks the growth of human melanoma, leukemia, lung, and prostate cancer cells in vitro.

A cell-permeable inhibitor of cathepsin B and L in vivo and in whole cells used to study the role of cathepsin B in neurodegeneration, cancer cell metastasis, necrosis, and rheumatoid arthritis.