Biologically Active Small Molecules

A prodrug of the potent, long-acting, and selective AT1 receptor antagonist, candesartan 4-16 mg/day effectively reduces diastolic blood pressure and has proved useful in the treatment of hypertension and diabetes.

A prodrug of the potent, long-acting, and selective AT1 receptor antagonist, candesartan 4-16 mg/day effectively reduces diastolic blood pressure and has proved useful in the treatment of hypertension and diabetes.

A prodrug of the potent, long-acting, and selective AT1 receptor antagonist, candesartan 4-16 mg/day effectively reduces diastolic blood pressure and has proved useful in the treatment of hypertension and diabetes.

A prodrug of the potent, long-acting, and selective AT1 receptor antagonist, candesartan 4-16 mg/day effectively reduces diastolic blood pressure and has proved useful in the treatment of hypertension and diabetes.

An irreversible quinazoline-based HER family tyrosine kinase inhibitor with IC50 values of 0.8, 19, and 7 nM for blocking in vitro activity of EGFR, HER2, and HER4, respectively inhibits the proliferation of various tumor cells.

An irreversible quinazoline-based HER family tyrosine kinase inhibitor with IC50 values of 0.8, 19, and 7 nM for blocking in vitro activity of EGFR, HER2, and HER4, respectively inhibits the proliferation of various tumor cells.

An irreversible quinazoline-based HER family tyrosine kinase inhibitor with IC50 values of 0.8, 19, and 7 nM for blocking in vitro activity of EGFR, HER2, and HER4, respectively inhibits the proliferation of various tumor cells.

An irreversible quinazoline-based HER family tyrosine kinase inhibitor with IC50 values of 0.8, 19, and 7 nM for blocking in vitro activity of EGFR, HER2, and HER4, respectively inhibits the proliferation of various tumor cells.

A PP1 and PP2A inhibitor with IC₅₀ values of 0.6 and 0.05 &microM, respectively.

A PP1 and PP2A inhibitor with IC₅₀ values of 0.6 and 0.05 &microM, respectively.

A PP1 and PP2A inhibitor with IC₅₀ values of 0.6 and 0.05 &microM, respectively.

A PP1 and PP2A inhibitor with IC₅₀ values of 0.6 and 0.05 &microM, respectively.