Biologically Active Small Molecules

A benzoylguanidine compound that selectively inhibits NHE-1 (IC₅₀s range from 0.03-3.4 &microM).

A benzoylguanidine compound that selectively inhibits NHE-1 (IC₅₀s range from 0.03-3.4 &microM).

A fluorinated pyrimidine and derivative of fluorouracil that has anti-neoplastic activity and is commonly used as adjuvant therapy following resection for some forms of cancer a potent inhibitor of acid ceramidase (IC₅₀ = 29 nM).

A fluorinated pyrimidine and derivative of fluorouracil that has anti-neoplastic activity and is commonly used as adjuvant therapy following resection for some forms of cancer a potent inhibitor of acid ceramidase (IC₅₀ = 29 nM).

A fluorinated pyrimidine and derivative of fluorouracil that has anti-neoplastic activity and is commonly used as adjuvant therapy following resection for some forms of cancer a potent inhibitor of acid ceramidase (IC₅₀ = 29 nM).

A nitrogen mustard &beta-chloro-nitrosourea compound used as an alkylating agent to form interstrand crosslinks in DNA, which leads to cancer cell cytotoxity and apoptosis also reported to inhibit glutathione reductase, thioredoxin reductase, and

A nitrogen mustard &beta-chloro-nitrosourea compound used as an alkylating agent to form interstrand crosslinks in DNA, which leads to cancer cell cytotoxity and apoptosis also reported to inhibit glutathione reductase, thioredoxin reductase, and

A nitrogen mustard &beta-chloro-nitrosourea compound used as an alkylating agent to form interstrand crosslinks in DNA, which leads to cancer cell cytotoxity and apoptosis also reported to inhibit glutathione reductase, thioredoxin reductase, and

Acetyl-L-carnitine is a derivative of carnitine that enables functions of CoA and plays a significant role in the maintenance of energy homeostasis. Acetyl-L-carnitine exhibits antidepressant, neuroprotective, analgesic, and antinociceptive

Acetyl-L-carnitine is a derivative of carnitine that enables functions of CoA and plays a significant role in the maintenance of energy homeostasis. Acetyl-L-carnitine exhibits antidepressant, neuroprotective, analgesic, and antinociceptive

Acetyl-L-carnitine is a derivative of carnitine that enables functions of CoA and plays a significant role in the maintenance of energy homeostasis. Acetyl-L-carnitine exhibits antidepressant, neuroprotective, analgesic, and antinociceptive

Carnosic acid is a diterpene found in Rosmarinus that exhibits antioxidative, anti-inflammatory, neuroprotective, cognition enhancing, and anticancer chemotherapeutic activities. Carnosic acid inhibits growth of colon adenocarcinoma cells and