Biologically Active Small Molecules

A selective inhibitor of 15-hydroxy PGDH (IC₅₀ = ~10 &microM).

A selective inhibitor of 15-hydroxy PGDH (IC₅₀ = ~10 &microM).

A selective inhibitor of 15-hydroxy PGDH (IC₅₀ = ~10 &microM).

An inhibitor of HDAC (IC₅₀ = 10 &microM).

An inhibitor of HDAC (IC₅₀ = 10 &microM).

An inhibitor of HDAC (IC₅₀ = 10 &microM).

An inhibitor of HDAC (IC₅₀ = 10 &microM).

A selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM approximately 580-fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions.

A selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM approximately 580-fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions.

A selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM approximately 580-fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions.

A selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM approximately 580-fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions.

Highly selective COX-2 inhibitor (IC₅₀ 50 &gt500 &microM (COX-1).