Biologically Active Small Molecules

CAY10462 is the hydrochloride salt of CAY10434 and selective inhibitor of the 20-HETE synthase CYP4A11 exhibiting an IC50 of 8.8 nM when tested in human renal microsomes.

CAY10462 is the hydrochloride salt of CAY10434 and selective inhibitor of the 20-HETE synthase CYP4A11 exhibiting an IC50 of 8.8 nM when tested in human renal microsomes.

A potent and selective AhR antagonist with a Ki value of 1.4 nM when tested in rabbit liver cytosol preparations.

A potent and selective AhR antagonist with a Ki value of 1.4 nM when tested in rabbit liver cytosol preparations.

A potent and selective AhR antagonist with a Ki value of 1.4 nM when tested in rabbit liver cytosol preparations.

A potent and selective AhR antagonist with a Ki value of 1.4 nM when tested in rabbit liver cytosol preparations.

An analog of resveratrol that acts as a potent and selective AhR agonist (Ki = 0.2 nM)

An analog of resveratrol that acts as a potent and selective AhR agonist (Ki = 0.2 nM)

An analog of resveratrol that acts as a potent and selective AhR agonist (Ki = 0.2 nM)

An analog of resveratrol that acts as a potent and selective AhR agonist (Ki = 0.2 nM)

The biological effects of PGD2 are transduced by at least two 7-transmembrane G-protein coupled receptors, designated DP1 and CRTH2/DP2. BAY-u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has

The biological effects of PGD2 are transduced by at least two 7-transmembrane G-protein coupled receptors, designated DP1 and CRTH2/DP2. BAY-u3405 (Ramatroban) is an approved human medication for the treatment of allergic rhinitis that has