Biologically Active Small Molecules

A potent HDAC inhibitor that inhibits HDAC2 and HDAC6 with IC₅₀ values of 0.119 and 434 nM ineffective against HDAC4 (IC₅₀ = &gt1,000 nM) inhibits the growth of HCT116 cells and HuT-78 cells (GI50 = 29.

A potent HDAC inhibitor that inhibits HDAC2 and HDAC6 with IC₅₀ values of 0.119 and 434 nM ineffective against HDAC4 (IC₅₀ = &gt1,000 nM) inhibits the growth of HCT116 cells and HuT-78 cells (GI50 = 29.

A potent HDAC inhibitor that inhibits HDAC2 and HDAC6 with IC₅₀ values of 0.119 and 434 nM ineffective against HDAC4 (IC₅₀ = &gt1,000 nM) inhibits the growth of HCT116 cells and HuT-78 cells (GI50 = 29.

A potent HDAC inhibitor that inhibits HDAC2 and HDAC6 with IC₅₀ values of 0.119 and 434 nM ineffective against HDAC4 (IC₅₀ = &gt1,000 nM) inhibits the growth of HCT116 cells and HuT-78 cells (GI50 = 29.

A potent EP4 agonist, triggering cAMP signaling with an EC₅₀ value of 0.8 nM.

A potent EP4 agonist, triggering cAMP signaling with an EC₅₀ value of 0.8 nM.

A potent EP4 agonist, triggering cAMP signaling with an EC₅₀ value of 0.8 nM.

A potent EP4 agonist, triggering cAMP signaling with an EC₅₀ value of 0.8 nM.

A cell-active analog of the lysine acetyltransferase inhibitor CPTH2 (Item No. 12086) that contains an alkyne moiety for use in click chemistry reactions used to study changes in nuclear architecture associated with cancer and certain laminopathies.

A cell-active analog of the lysine acetyltransferase inhibitor CPTH2 (Item No. 12086) that contains an alkyne moiety for use in click chemistry reactions used to study changes in nuclear architecture associated with cancer and certain laminopathies.

A cell-active analog of the lysine acetyltransferase inhibitor CPTH2 (Item No. 12086) that contains an alkyne moiety for use in click chemistry reactions used to study changes in nuclear architecture associated with cancer and certain laminopathies.

A cell-active analog of the lysine acetyltransferase inhibitor CPTH2 (Item No. 12086) that contains an alkyne moiety for use in click chemistry reactions used to study changes in nuclear architecture associated with cancer and certain laminopathies.