Biologically Active Small Molecules

A DCA trimer that is at least 10-fold more cytotoxic against leukemia cell lines than DCA significantly reduces both basal and maximal respiration in leukemia cells.

A DCA trimer that is at least 10-fold more cytotoxic against leukemia cell lines than DCA significantly reduces both basal and maximal respiration in leukemia cells.

A DCA trimer that is at least 10-fold more cytotoxic against leukemia cell lines than DCA significantly reduces both basal and maximal respiration in leukemia cells.

A DCA trimer that is at least 10-fold more cytotoxic against leukemia cell lines than DCA significantly reduces both basal and maximal respiration in leukemia cells.

A potent inhibitor of HCV infection (EC₅₀ = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.

A potent inhibitor of HCV infection (EC₅₀ = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.

A potent inhibitor of HCV infection (EC₅₀ = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.

A substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria displays MIC99 values of 2.9, 11.

A substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria displays MIC99 values of 2.9, 11.

A substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria displays MIC99 values of 2.9, 11.

A substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria displays MIC99 values of 2.9, 11.

A selective inhibitor of the breast cancer resistance protein ABCG2 (IC₅₀ = 0.23 &microM).