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20469-10A selective inhibitor of the breast cancer resistance protein ABCG2 (IC<sub>50</sub> = 0.23 µM).
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20469-25A selective inhibitor of the breast cancer resistance protein ABCG2 (IC<sub>50</sub> = 0.23 µM).
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20469-5A selective inhibitor of the breast cancer resistance protein ABCG2 (IC<sub>50</sub> = 0.23 µM).
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10004985-1A nutlin-3 analog inhibits the growth of HCT116 cells at high concentrations (IC50 = ~7 µM) promotes the growth of HCT-116 cells ~20% at concentrations at or below 1 µM.
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10004985-10A nutlin-3 analog inhibits the growth of HCT116 cells at high concentrations (IC50 = ~7 µM) promotes the growth of HCT-116 cells ~20% at concentrations at or below 1 µM.
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10004985-5A nutlin-3 analog inhibits the growth of HCT116 cells at high concentrations (IC50 = ~7 µM) promotes the growth of HCT-116 cells ~20% at concentrations at or below 1 µM.
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10005002-1A nutlin-3 analog inhibits the growth of HCT116 cells at high concentrations (IC50 = ~8 µM) promotes the growth of HCT116 cells ~40% at concentrations between 5-100 nM.
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10005002-10A nutlin-3 analog inhibits the growth of HCT116 cells at high concentrations (IC50 = ~8 µM) promotes the growth of HCT116 cells ~40% at concentrations between 5-100 nM.
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10005002-5A nutlin-3 analog inhibits the growth of HCT116 cells at high concentrations (IC50 = ~8 µM) promotes the growth of HCT116 cells ~40% at concentrations between 5-100 nM.
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19311-1CB-5083 is an orally bioavailable inhibitor of p97 (IC<sub>50</sub> = 11 nM), a transitional endoplasmic reticulum ATPase also known as valosin-containing protein (VCP). It disrupts cellular protein homeostasis and demonstrates anti-tumor activity
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19311-10CB-5083 is an orally bioavailable inhibitor of p97 (IC<sub>50</sub> = 11 nM), a transitional endoplasmic reticulum ATPase also known as valosin-containing protein (VCP). It disrupts cellular protein homeostasis and demonstrates anti-tumor activity
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19311-25CB-5083 is an orally bioavailable inhibitor of p97 (IC<sub>50</sub> = 11 nM), a transitional endoplasmic reticulum ATPase also known as valosin-containing protein (VCP). It disrupts cellular protein homeostasis and demonstrates anti-tumor activity