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19311-5CB-5083 is an orally bioavailable inhibitor of p97 (IC<sub>50</sub> = 11 nM), a transitional endoplasmic reticulum ATPase also known as valosin-containing protein (VCP). It disrupts cellular protein homeostasis and demonstrates anti-tumor activity
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A7085-5 mg
Thomas Scientific
CB1 and TRPV1 agonist. It decreases immobility time in the forced swim test and tail suspension test, increases lung tidal volume, diaphragm activity, and mean arterial blood pressure, and inhibits lymphocyte proliferation.
Price: $224.02List Price: $248.92Arvanil is an agonist at transient receptor potential vanilloid 1 (TRPV1) channels and cannabinoid 1 (CB1) receptors. Arvanil exhibits antidepressant, hypertensive, immunosuppressive, anti-inflammatory, antiemetic, and anticancer activities. -
13172-10HDAC1 and HDAC3 inhibitor (ID50 = 0.01 and 0.07 &muM, respectively, in vitro) induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 &muM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/kg.
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13172-25HDAC1 and HDAC3 inhibitor (ID50 = 0.01 and 0.07 &muM, respectively, in vitro) induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 &muM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/kg.
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13172-5HDAC1 and HDAC3 inhibitor (ID50 = 0.01 and 0.07 &muM, respectively, in vitro) induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 &muM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/kg.
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19373-1A water soluble and metabolically stable curaxin that activates p53 with an EC<sub>50</sub> value of 0.37 µM and inhibits NF-&kappaB with an EC<sub>50</sub> value of 0.
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19373-10A water soluble and metabolically stable curaxin that activates p53 with an EC<sub>50</sub> value of 0.37 µM and inhibits NF-&kappaB with an EC<sub>50</sub> value of 0.
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19373-5A water soluble and metabolically stable curaxin that activates p53 with an EC<sub>50</sub> value of 0.37 µM and inhibits NF-&kappaB with an EC<sub>50</sub> value of 0.
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19110-1A water soluble and metabolically stable curaxin that activates p53 with an EC<sub>50</sub> value of 0.37 µM and inhibits NF-&kappaB with an EC<sub>50</sub> of 0.47 µM has broad anticancer activity in mice when administered orally.
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19110-10A water soluble and metabolically stable curaxin that activates p53 with an EC<sub>50</sub> value of 0.37 µM and inhibits NF-&kappaB with an EC<sub>50</sub> of 0.47 µM has broad anticancer activity in mice when administered orally.
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19110-5A water soluble and metabolically stable curaxin that activates p53 with an EC<sub>50</sub> value of 0.37 µM and inhibits NF-&kappaB with an EC<sub>50</sub> of 0.47 µM has broad anticancer activity in mice when administered orally.
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19236-1An inhibitor of PHGDH, inhibiting serine synthesis from 3-PG in cells (IC<sub>50</sub> = 33 µM) inhibits the proliferation of cancer cells by blocking de novo serine synthesis.