Biologically Active Small Molecules

A third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls increases EAAT-2 pump expression in the CNS and reduces glutamatergic toxicity in both in vitro and in vivo

A third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls increases EAAT-2 pump expression in the CNS and reduces glutamatergic toxicity in both in vitro and in vivo

A bioactive compound that inhibits the growth of bacteria and mycobacteria (minimal inhibitory concentration = 0.05 &mug/ml) suppresses TNF-&alpha-stimulated IL-8 production in HUVECs (IC₅₀ = 0.01 &mug/ml).

A bioactive compound that inhibits the growth of bacteria and mycobacteria (minimal inhibitory concentration = 0.05 &mug/ml) suppresses TNF-&alpha-stimulated IL-8 production in HUVECs (IC₅₀ = 0.01 &mug/ml).

A bioactive compound that inhibits the growth of bacteria and mycobacteria (minimal inhibitory concentration = 0.05 &mug/ml) suppresses TNF-&alpha-stimulated IL-8 production in HUVECs (IC₅₀ = 0.01 &mug/ml).

A variety of natural products from plant sources, particularly flavonoids, have long been observed to have antioxidant activity with potential benefits for human health. Antioxidant triterpenes are less common.

A variety of natural products from plant sources, particularly flavonoids, have long been observed to have antioxidant activity with potential benefits for human health. Antioxidant triterpenes are less common.

A variety of natural products from plant sources, particularly flavonoids, have long been observed to have antioxidant activity with potential benefits for human health. Antioxidant triterpenes are less common.

A variety of natural products from plant sources, particularly flavonoids, have long been observed to have antioxidant activity with potential benefits for human health. Antioxidant triterpenes are less common.

An anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits COX-2 (IC50s = 22.9 and 0.

An anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits COX-2 (IC50s = 22.9 and 0.

An anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits COX-2 (IC50s = 22.9 and 0.