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18406-5A potent inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that induces concentration-dependent growth inhibition or cytotoxicity of ALK-positive cancer cells inhibits ALK tyrosine phosphorylation in tumor xenografts in mice for more than 12 hours
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18776-1A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC<sub>50</sub>s = 78 and 60 nM, respectively)
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18776-10A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC<sub>50</sub>s = 78 and 60 nM, respectively)
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18776-5A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC<sub>50</sub>s = 78 and 60 nM, respectively)
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18776-500A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC<sub>50</sub>s = 78 and 60 nM, respectively)
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16732-1A potent, orally available inhibitor of JAK2 (IC<sub>50</sub> = 1.3 nM) reduces the production of inflammatory cytokines and blocks disease development in mouse models of lupus and arthritis induces regression of established colorectal tumors in
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16732-5A potent, orally available inhibitor of JAK2 (IC<sub>50</sub> = 1.3 nM) reduces the production of inflammatory cytokines and blocks disease development in mouse models of lupus and arthritis induces regression of established colorectal tumors in
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16732-500A potent, orally available inhibitor of JAK2 (IC<sub>50</sub> = 1.3 nM) reduces the production of inflammatory cytokines and blocks disease development in mouse models of lupus and arthritis induces regression of established colorectal tumors in
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9000595-1An internal standard for the quantification of CEP-Lysine by GC- or LC-MS.
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9000595-500An internal standard for the quantification of CEP-Lysine by GC- or LC-MS.
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9002009-1A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.
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9002009-10A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.