Biologically Active Small Molecules

A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.

A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.

A biscoclaurine alkaloid that can decrease the fluidity of biological membranes exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models.

A biscoclaurine alkaloid that can decrease the fluidity of biological membranes exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models.

A biscoclaurine alkaloid that can decrease the fluidity of biological membranes exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models.

A biscoclaurine alkaloid that can decrease the fluidity of biological membranes exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models.

A non-lipid inhibitor of cellular ceramidase activity (IC50 = 28 &muM in a cell-based assay) induces the accumulation of endogenous ceramide species and decreases intracellular levels of sphingosine and S1P inhibits cell proliferation of ovarian

A non-lipid inhibitor of cellular ceramidase activity (IC50 = 28 &muM in a cell-based assay) induces the accumulation of endogenous ceramide species and decreases intracellular levels of sphingosine and S1P inhibits cell proliferation of ovarian

A non-lipid inhibitor of cellular ceramidase activity (IC50 = 28 &muM in a cell-based assay) induces the accumulation of endogenous ceramide species and decreases intracellular levels of sphingosine and S1P inhibits cell proliferation of ovarian

A non-lipid inhibitor of cellular ceramidase activity (IC50 = 28 &muM in a cell-based assay) induces the accumulation of endogenous ceramide species and decreases intracellular levels of sphingosine and S1P inhibits cell proliferation of ovarian

A natural antifungal phytotoxin that selectively and potently inhibits fungal Pkc1, which are central to cell wall integrity (IC₅₀ = 25 nM for Candida Pkc1) potently inhibits MAPK-interacting kinases Mnk1 and Mnk2 (IC₅₀ = 115

A natural antifungal phytotoxin that selectively and potently inhibits fungal Pkc1, which are central to cell wall integrity (IC₅₀ = 25 nM for Candida Pkc1) potently inhibits MAPK-interacting kinases Mnk1 and Mnk2 (IC₅₀ = 115