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18658-25A synthetic analog of retinoic acid that binds to retinoic acid receptors with similar efficiency as retinoic acid (Kis in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM).
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18658-5A synthetic analog of retinoic acid that binds to retinoic acid receptors with similar efficiency as retinoic acid (Kis in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM).
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17120-1A potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC<sub>50</sub>s = 9.3, 7.
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17120-10A potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC<sub>50</sub>s = 9.3, 7.
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17120-25A potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC<sub>50</sub>s = 9.3, 7.
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17120-5A potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC<sub>50</sub>s = 9.3, 7.
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18516-1An orally available, selective inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that also inhibits F1174L, R1275Q, and L1196M mutants of ALK (IC<sub>50</sub>s = 1.
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18516-10An orally available, selective inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that also inhibits F1174L, R1275Q, and L1196M mutants of ALK (IC<sub>50</sub>s = 1.
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18516-5An orally available, selective inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that also inhibits F1174L, R1275Q, and L1196M mutants of ALK (IC<sub>50</sub>s = 1.
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13156-1A fungal mycotoxin that inhibits the Lys9-specific histone methyltransferases SU(VAR)3-9 (IC<sub>50</sub> = 0.8 &muM), G9a (IC<sub>50</sub> = 2.5 &muM), and DIM5 (IC<sub>50 </sub>= 3 &muM).
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13156-10A fungal mycotoxin that inhibits the Lys9-specific histone methyltransferases SU(VAR)3-9 (IC<sub>50</sub> = 0.8 &muM), G9a (IC<sub>50</sub> = 2.5 &muM), and DIM5 (IC<sub>50 </sub>= 3 &muM).
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13156-5A fungal mycotoxin that inhibits the Lys9-specific histone methyltransferases SU(VAR)3-9 (IC<sub>50</sub> = 0.8 &muM), G9a (IC<sub>50</sub> = 2.5 &muM), and DIM5 (IC<sub>50 </sub>= 3 &muM).