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14455-5A selective inhibitor of PDE3A and PDE3B (IC<sub>50</sub>s = 27 and 50 nM, respectively) inhibits thrombin-induced platelet aggregation (IC<sub>50</sub> = 1.1 &muM).
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15035-10An anti-thrombotic agent which inhibits ADP-dependent platelet aggregation by selective and specific inhibition of cyclic nucleotide PDE3 (IC<sub>50</sub> = 200 nM).
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15035-100An anti-thrombotic agent which inhibits ADP-dependent platelet aggregation by selective and specific inhibition of cyclic nucleotide PDE3 (IC<sub>50</sub> = 200 nM).
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15035-250An anti-thrombotic agent which inhibits ADP-dependent platelet aggregation by selective and specific inhibition of cyclic nucleotide PDE3 (IC<sub>50</sub> = 200 nM).
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15035-50An anti-thrombotic agent which inhibits ADP-dependent platelet aggregation by selective and specific inhibition of cyclic nucleotide PDE3 (IC<sub>50</sub> = 200 nM).
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15613-10A potent agonist of &beta-adrenergic receptors (pEC<sub>50</sub> = 8.13, 8.78, and 6.62 for human &beta1, &beta2, and &beta3, respectively).
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15613-50A potent agonist of &beta-adrenergic receptors (pEC<sub>50</sub> = 8.13, 8.78, and 6.62 for human &beta1, &beta2, and &beta3, respectively).
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18743-10An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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18743-25An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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18743-5An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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18743-50An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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16042-10A calcimimetic that allosterically activates the calcium-sensing receptor (CaSR pEC<sub>50</sub> = 7.3 in HEK293T cells expressing CaSR) inhibiting parathyroid hormone secretion.