Biologically Active Small Molecules

An antibiotic which binds the bacterial 50S ribosomal subunit and interferes with protein synthesis effective against anaerobes and is commonly used against Gram positive bacteria.

A selective histamine H3 receptor antagonist that crosses the blood-brain barrier inhibits histamine binding in rat brain with an ED50 value of 10.5 mg/kg.

A selective histamine H3 receptor antagonist that crosses the blood-brain barrier inhibits histamine binding in rat brain with an ED50 value of 10.5 mg/kg.

A selective histamine H3 receptor antagonist that crosses the blood-brain barrier inhibits histamine binding in rat brain with an ED50 value of 10.5 mg/kg.

A selective histamine H3 receptor antagonist that crosses the blood-brain barrier inhibits histamine binding in rat brain with an ED50 value of 10.5 mg/kg.

A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC₅₀ = 1.34 &microM) and bone resorption is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce

A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC₅₀ = 1.34 &microM) and bone resorption is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce

A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC₅₀ = 1.34 &microM) and bone resorption is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce

A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC₅₀ = 1.34 &microM) and bone resorption is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce

A nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase-&alpha (IC₅₀s = 65 and 3.9 nM, respectively) and is cytotoxic to K562 myelogenous leukemia cells (IC₅₀ = 5 nM) as well as various other leukemias

A nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase-&alpha (IC₅₀s = 65 and 3.9 nM, respectively) and is cytotoxic to K562 myelogenous leukemia cells (IC₅₀ = 5 nM) as well as various other leukemias

A nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase-&alpha (IC₅₀s = 65 and 3.9 nM, respectively) and is cytotoxic to K562 myelogenous leukemia cells (IC₅₀ = 5 nM) as well as various other leukemias