Biologically Active Small Molecules

A centrally acting &alpha2-adrenergic receptor agonist that decreases peripheral vascular resistance by centrally inhibiting sympathetic nerve activity also acts as an agonist of the imidazoline (I1) receptor (Ki = 4-8 nM).

A thiazide-like diuretic that inhibits sodium/chloride cotransporters in the proximal convoluted tubule of the kidney, which prevents the reabsorption of sodium and chloride.

A major inactive metabolite of clopidogrel that is used as a reference standard for quantitative analysis of clopidogrel metabolism.

A major inactive metabolite of clopidogrel that is used as a reference standard for quantitative analysis of clopidogrel metabolism.

A major inactive metabolite of clopidogrel that is used as a reference standard for quantitative analysis of clopidogrel metabolism.

A major inactive metabolite of clopidogrel that is used as a reference standard for quantitative analysis of clopidogrel metabolism.

Cloprostenol (sodium salt) is a more water solute, crystalline form of cloprostenol than the free acid.

Cloprostenol (sodium salt) is a more water solute, crystalline form of cloprostenol than the free acid.

Cloprostenol (sodium salt) is a more water solute, crystalline form of cloprostenol than the free acid.

A potent MAO inhibitor that preferentially targets MAO-A over MAO-B (Kis = 0.054 and 58 &microM, respectively) also inhibits the sigma receptor &sigma1 on Jurkat human T lymphocyte cells (IC₅₀ = 31 nM).

A potent MAO inhibitor that preferentially targets MAO-A over MAO-B (Kis = 0.054 and 58 &microM, respectively) also inhibits the sigma receptor &sigma1 on Jurkat human T lymphocyte cells (IC₅₀ = 31 nM).

A potent MAO inhibitor that preferentially targets MAO-A over MAO-B (Kis = 0.054 and 58 &microM, respectively) also inhibits the sigma receptor &sigma1 on Jurkat human T lymphocyte cells (IC₅₀ = 31 nM).