Biologically Active Small Molecules

Selective inhibitor of vacuolar type H+-ATPases (IC₅₀ = 5 nM) blocks the acidification of vacuolar organelles as well as early to late endosomal transport interferes with bone resorption, maturation of CD8 T lymphocytes, and the

Selective inhibitor of vacuolar type H+-ATPases (IC₅₀ = 5 nM) blocks the acidification of vacuolar organelles as well as early to late endosomal transport interferes with bone resorption, maturation of CD8 T lymphocytes, and the

A plant lectin that selectively cross-links cell-surface glycoproteins and affects the initiation of cell agglutination, mitogenesis, and apoptosis widely used in affinity chromatography purifications of various glycoproteins and cellular

A plant lectin that selectively cross-links cell-surface glycoproteins and affects the initiation of cell agglutination, mitogenesis, and apoptosis widely used in affinity chromatography purifications of various glycoproteins and cellular

A plant lectin that selectively cross-links cell-surface glycoproteins and affects the initiation of cell agglutination, mitogenesis, and apoptosis widely used in affinity chromatography purifications of various glycoproteins and cellular

An irreversible inhibitor of GBA (IC₅₀ = 9 &muM) does not inhibit non-lysosomal glucosylceramidase or cytosolic &beta-glucosidase.

An irreversible inhibitor of GBA (IC₅₀ = 9 &muM) does not inhibit non-lysosomal glucosylceramidase or cytosolic &beta-glucosidase.

An irreversible inhibitor of GBA (IC₅₀ = 9 &muM) does not inhibit non-lysosomal glucosylceramidase or cytosolic &beta-glucosidase.

A naturally occurring steroid alkaloid that acts as a potent histamine H3 receptor antagonist (Kis = 5.2 and 24.5 nM for rat and human, respectively) that efficiently crosses the blood-brain barrier but has a poor rate of CNS clearance.

A naturally occurring steroid alkaloid that acts as a potent histamine H3 receptor antagonist (Kis = 5.2 and 24.5 nM for rat and human, respectively) that efficiently crosses the blood-brain barrier but has a poor rate of CNS clearance.

A naturally occurring steroid alkaloid that acts as a potent histamine H3 receptor antagonist (Kis = 5.2 and 24.5 nM for rat and human, respectively) that efficiently crosses the blood-brain barrier but has a poor rate of CNS clearance.

Conjugate of N-acetyl-cysteine and benzylisothiocyanate. It