Biologically Active Small Molecules

A natural sesquiterpene lactone that reduces growth (EC₅₀ = 3-35 &muM) and induces apoptosis in assorted cancer cell lines inhibits the activation of Akt (15 &muM) in endometriotic epithelial cells and STAT3 activation in THP-1 cells

A natural sesquiterpene lactone that reduces growth (EC₅₀ = 3-35 &muM) and induces apoptosis in assorted cancer cell lines inhibits the activation of Akt (15 &muM) in endometriotic epithelial cells and STAT3 activation in THP-1 cells

A natural sesquiterpene lactone that reduces growth (EC₅₀ = 3-35 &muM) and induces apoptosis in assorted cancer cell lines inhibits the activation of Akt (15 &muM) in endometriotic epithelial cells and STAT3 activation in THP-1 cells

A natural sesquiterpene lactone that reduces growth (EC₅₀ = 3-35 &muM) and induces apoptosis in assorted cancer cell lines inhibits the activation of Akt (15 &muM) in endometriotic epithelial cells and STAT3 activation in THP-1 cells

An orally available activator of mutant forms of p53 induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar

An orally available activator of mutant forms of p53 induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar

An orally available activator of mutant forms of p53 induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar

An orally available activator of mutant forms of p53 induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar

A fluorescent probe that can react with ONOO-, HOCl, and H2O2 in a similar manner to CBA, yet is formulated for improved solubility.

A fluorescent probe that can react with ONOO-, HOCl, and H2O2 in a similar manner to CBA, yet is formulated for improved solubility.

A fluorescent probe that can react with ONOO-, HOCl, and H2O2 in a similar manner to CBA, yet is formulated for improved solubility.

A fluorescent probe that can react with ONOO-, HOCl, and H2O2 in a similar manner to CBA, yet is formulated for improved solubility.