Biologically Active Small Molecules

An inhibitor of protein synthesis in eukaryotes (IC₅₀ = 5-50 &muM) that functions by interfering with translational elongation can either induce or inhibit apoptosis depending on cell type.

A natural steroidal alkaloid that inhibits signaling through the Hh pathway at the level of the pathway activator Smo inhibits Hh-dependent expression of Pax7 with an IC50 value of 24 nM has potential applications in the treatment of cancer.

A natural steroidal alkaloid that inhibits signaling through the Hh pathway at the level of the pathway activator Smo inhibits Hh-dependent expression of Pax7 with an IC50 value of 24 nM has potential applications in the treatment of cancer.

A natural steroidal alkaloid that inhibits signaling through the Hh pathway at the level of the pathway activator Smo inhibits Hh-dependent expression of Pax7 with an IC50 value of 24 nM has potential applications in the treatment of cancer.

This mixture contains all of the major UV-absorbing cyclopentenone prostaglandins and their precursors. Contents: 100 &microg of each compound Prostaglandin A2 (Item No.

A nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.

A nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.

A nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.

A nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.

A mycotoxin that specifically and reversibly inhibits sarco-endoplasmic reticulum Ca2+-ATPases (SERCA IC50 = 0.6 &muM) effectively inhibits SERCA in intact tissue, in smooth muscle and endothelium, as well as in isolated cells.

A mycotoxin that specifically and reversibly inhibits sarco-endoplasmic reticulum Ca2+-ATPases (SERCA IC50 = 0.6 &muM) effectively inhibits SERCA in intact tissue, in smooth muscle and endothelium, as well as in isolated cells.

A mycotoxin that specifically and reversibly inhibits sarco-endoplasmic reticulum Ca2+-ATPases (SERCA IC50 = 0.6 &muM) effectively inhibits SERCA in intact tissue, in smooth muscle and endothelium, as well as in isolated cells.