Biologically Active Small Molecules

This mixture contains all of the primary cysteinyl-leukotrienes derived from arachidonic acid. Contents: Leukotriene C4, Leukotriene D4, Leukotriene E4, Leukotriene F4, and N-acetyl Leukotriene E4 (5 &microg each).

This mixture contains all primary cysteinyl leukotrienes derived from arachidonic acid and also includes Prostaglandin B2. Contents: Leukotriene C4, Leukotriene D4, Leukotriene E4, Leukotriene F4, N-acetyl Leukotriene E4 (5 &microg each) and

An ATP-competitive inhibitor of JAK1 and JAK2 (IC₅₀s = 11 and 18 nM, respectively) causes growth suppression and apoptosis in JAK2-dependent hematopoietic cell lines is efficacious in a mouse model of JAK2V617F-dependent

An ATP-competitive inhibitor of JAK1 and JAK2 (IC₅₀s = 11 and 18 nM, respectively) causes growth suppression and apoptosis in JAK2-dependent hematopoietic cell lines is efficacious in a mouse model of JAK2V617F-dependent

An ATP-competitive inhibitor of JAK1 and JAK2 (IC₅₀s = 11 and 18 nM, respectively) causes growth suppression and apoptosis in JAK2-dependent hematopoietic cell lines is efficacious in a mouse model of JAK2V617F-dependent

An ATP-competitive inhibitor of JAK1 and JAK2 (IC₅₀s = 11 and 18 nM, respectively) causes growth suppression and apoptosis in JAK2-dependent hematopoietic cell lines is efficacious in a mouse model of JAK2V617F-dependent

An orally available inhibitor of microtubule polymerization (IC₅₀ = ~3 &microM) that blocks cell cycling at the G2-M phase, which leads to cell death cytotoxic to a range of cancer cell lines (IC₅₀s = 9-101 nM) and

An orally available inhibitor of microtubule polymerization (IC₅₀ = ~3 &microM) that blocks cell cycling at the G2-M phase, which leads to cell death cytotoxic to a range of cancer cell lines (IC₅₀s = 9-101 nM) and

An orally available inhibitor of microtubule polymerization (IC₅₀ = ~3 &microM) that blocks cell cycling at the G2-M phase, which leads to cell death cytotoxic to a range of cancer cell lines (IC₅₀s = 9-101 nM) and

An orally available inhibitor of microtubule polymerization (IC₅₀ = ~3 &microM) that blocks cell cycling at the G2-M phase, which leads to cell death cytotoxic to a range of cancer cell lines (IC₅₀s = 9-101 nM) and

A nucleoside analog that differs from cytosine by the presence of a hydroxyl group at the 2&rsquo position of the sugar residue triphosphorylated in vivo to produce ara-CTP, a competitive inhibitor of DNA polymerases &alpha and &beta (Kis = 4

A nucleoside analog that differs from cytosine by the presence of a hydroxyl group at the 2&rsquo position of the sugar residue triphosphorylated in vivo to produce ara-CTP, a competitive inhibitor of DNA polymerases &alpha and &beta (Kis = 4