Biologically Active Small Molecules

An analog of L-carnitine that, in the range of 0.25-1 mM, inhibits the uptake of L-carnitine by cells.

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An analog of ceramide that inhibits alkaline ceramidase (IC50 ~5 &microM) suppresses growth of HL-60 cancer cells in culture.

An analog of ceramide that inhibits alkaline ceramidase (IC50 ~5 &microM) suppresses growth of HL-60 cancer cells in culture.

An analog of ceramide that inhibits alkaline ceramidase (IC50 ~5 &microM) suppresses growth of HL-60 cancer cells in culture.

An analog of ceramide that inhibits alkaline ceramidase (IC50 ~5 &microM) suppresses growth of HL-60 cancer cells in culture.

D-erythro-Sphinganine is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including

D-erythro-Sphinganine is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including

D-erythro-Sphinganine is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including