Biologically Active Small Molecules

Ins(4,5)P2 is a metabolite of Ins(1,4,5)P3 that lacks a phosphate at the 1&#39 position. Ins(4,5)P2 formation has been reported as an intermediate in the metabolism Ins(1,4,5)P3 in GH3 pituitary cells.

Ins(4)P1 is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells

Ins(4)P1 is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells

Ins(4)P1 is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3, is a second messenger produced in cells

A potent ceramidase inhibitor that induces apoptosis in human colorectal cancer, keratinocyte, and melanoma cell lines produces approximately 50% cell non-viability at 10 &microM and &gt80% cell death at 100 &microM.

A potent ceramidase inhibitor that induces apoptosis in human colorectal cancer, keratinocyte, and melanoma cell lines produces approximately 50% cell non-viability at 10 &microM and &gt80% cell death at 100 &microM.

A potent ceramidase inhibitor that induces apoptosis in human colorectal cancer, keratinocyte, and melanoma cell lines produces approximately 50% cell non-viability at 10 &microM and &gt80% cell death at 100 &microM.

A potent ceramidase inhibitor that induces apoptosis in human colorectal cancer, keratinocyte, and melanoma cell lines produces approximately 50% cell non-viability at 10 &microM and &gt80% cell death at 100 &microM.

The inactive enantiomer of L-NMMA used as a control compound to explore non-specific effects of L-NMMA.

The inactive enantiomer of L-NMMA used as a control compound to explore non-specific effects of L-NMMA.

The inactive enantiomer of L-NMMA used as a control compound to explore non-specific effects of L-NMMA.

A precursor in the biosynthesis of coenzyme A.