Biologically Active Small Molecules

An inhibitor of CETP inhibits plasma CETP with an IC₅₀ value of 9 &microM in rabbits given an atherogenic diet, increases HDL, decreases VLDL, and attenuates induced atherosclerosis in humans, inhibits CETP activity and increases HDL

A streptogramin antibiotic that is usually combined with another streptogramin antibiotic, quinupristin, to synergistically kill Gram-positive bacteria.

A streptogramin antibiotic that is usually combined with another streptogramin antibiotic, quinupristin, to synergistically kill Gram-positive bacteria.

A selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A (IC50s = 1.5, 0.55, and 2.1 &muM, respectively).

A selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A (IC50s = 1.5, 0.55, and 2.1 &muM, respectively).

A selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A (IC50s = 1.5, 0.55, and 2.1 &muM, respectively).

DAN-1 EE is a fluorescent indicator for the bioimaging of NO. DAN-1 EE is a cell permeable derivative of DAN, a molecule which has been used extensively in the quantitation of nitrate and nitrite using fluorescence spectroscopy.

DAN-1 EE is a fluorescent indicator for the bioimaging of NO. DAN-1 EE is a cell permeable derivative of DAN, a molecule which has been used extensively in the quantitation of nitrate and nitrite using fluorescence spectroscopy.

DAN-1 EE is a fluorescent indicator for the bioimaging of NO. DAN-1 EE is a cell permeable derivative of DAN, a molecule which has been used extensively in the quantitation of nitrate and nitrite using fluorescence spectroscopy.

DAN-1 EE is a fluorescent indicator for the bioimaging of NO. DAN-1 EE is a cell permeable derivative of DAN, a molecule which has been used extensively in the quantitation of nitrate and nitrite using fluorescence spectroscopy.

A derivative of testosterone and ethisterone that binds androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone possesses weak androgenic effects and inhibits the production of gonadotropins.

A derivative of testosterone and ethisterone that binds androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone possesses weak androgenic effects and inhibits the production of gonadotropins.