Biologically Active Small Molecules

,p>Decitabine is a deoxycytidine analog that is incorporated into DNA, inhibiting DNA methyltransferase (DNMT1/3A/3B) activity. This demethylating agent is clinically used to treat myelodysplastic syndromes.

,p>Decitabine is a deoxycytidine analog that is incorporated into DNA, inhibiting DNA methyltransferase (DNMT1/3A/3B) activity. This demethylating agent is clinically used to treat myelodysplastic syndromes.

An intermediate for the synthesis of glucosylceramide synthase inhibitors such as 1-dNM, a glucose analog that potently inhibits &alpha-glucosidase I and II.

An intermediate for the synthesis of glucosylceramide synthase inhibitors such as 1-dNM, a glucose analog that potently inhibits &alpha-glucosidase I and II.

An intermediate for the synthesis of glucosylceramide synthase inhibitors such as 1-dNM, a glucose analog that potently inhibits &alpha-glucosidase I and II.

An intermediate for the synthesis of glucosylceramide synthase inhibitors such as 1-dNM, a glucose analog that potently inhibits &alpha-glucosidase I and II.

A biotinylated form of DEPMPO, which is used to spin trap reactive O-, N-, S-, and C-centered radicals offers monitored biodistribution in cells, tissues and organs when used with an avidin-conjugated reporter binds free radicals on proteins,

A biotinylated form of DEPMPO, which is used to spin trap reactive O-, N-, S-, and C-centered radicals offers monitored biodistribution in cells, tissues and organs when used with an avidin-conjugated reporter binds free radicals on proteins,

A biotinylated form of DEPMPO, which is used to spin trap reactive O-, N-, S-, and C-centered radicals offers monitored biodistribution in cells, tissues and organs when used with an avidin-conjugated reporter binds free radicals on proteins,

A biotinylated form of DEPMPO, which is used to spin trap reactive O-, N-, S-, and C-centered radicals offers monitored biodistribution in cells, tissues and organs when used with an avidin-conjugated reporter binds free radicals on proteins,

Anabasine is an alkaloid originally found in species of Nicotiana it is a structural isomer of nicotine. Anabasine inhibits aromatase and nicotinic acetylcholine receptors (nAChRs) and may produce a depolarizing neuromuscular junction (NMJ) block.

Anabasine is an alkaloid originally found in species of Nicotiana it is a structural isomer of nicotine. Anabasine inhibits aromatase and nicotinic acetylcholine receptors (nAChRs) and may produce a depolarizing neuromuscular junction (NMJ) block.