Biologically Active Small Molecules

A precursor of rhein, which inhibits IL-1&beta signaling at 10 &microM, suppresses signaling through NF-&kappaB and AP-1, and reduces the expression of MMP-1 and MMP-13 down-regulates the expression of the IL-1&beta receptor, enhances the

A potent, trichothecene mycotoxin produced by certain Fusarium strains that is toxic to fungi, plants, animals, and various mammalian tissue cultures via inhibition de novo protein synthesis.

A potent, trichothecene mycotoxin produced by certain Fusarium strains that is toxic to fungi, plants, animals, and various mammalian tissue cultures via inhibition de novo protein synthesis.

A potent, trichothecene mycotoxin produced by certain Fusarium strains that is toxic to fungi, plants, animals, and various mammalian tissue cultures via inhibition de novo protein synthesis.

An organosulfur compound derived from allicin converted, in the presence of thiols, to the gaseous mediator H2S serves as a thiol-dependent H2S donor in biological systems.

An organosulfur compound derived from allicin converted, in the presence of thiols, to the gaseous mediator H2S serves as a thiol-dependent H2S donor in biological systems.

An organosulfur compound derived from allicin converted, in the presence of thiols, to the gaseous mediator H2S serves as a thiol-dependent H2S donor in biological systems.

An organic polysulfide compound found in garlic that acts as an H2S donor reduces the survival of prostate cancer PC-3 cells (IC50 = 22 &muM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 &muM) suppresses the

An organic polysulfide compound found in garlic that acts as an H2S donor reduces the survival of prostate cancer PC-3 cells (IC50 = 22 &muM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 &muM) suppresses the

An organic polysulfide compound found in garlic that acts as an H2S donor reduces the survival of prostate cancer PC-3 cells (IC50 = 22 &muM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 &muM) suppresses the

An organic polysulfide compound found in garlic that acts as an H2S donor reduces the survival of prostate cancer PC-3 cells (IC50 = 22 &muM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 &muM) suppresses the

A potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions relaxes rat aorta rings (ED₅₀ = 19.3 &muM) and has been used as a vasodilator in the treatment of