Biologically Active Small Molecules

An NSAID that inhibits both COX-1 (IC₅₀ = 113 &microM) and COX-2 (IC₅₀s = 8.2 and 134 &microM for human whole blood assay and human-modified whole blood assays, respectively).

An NSAID that inhibits both COX-1 (IC₅₀ = 113 &microM) and COX-2 (IC₅₀s = 8.2 and 134 &microM for human whole blood assay and human-modified whole blood assays, respectively).

A non-ionic detergent used to solubilize membrane-bound proteins, to precipitate cholesterol, and to permeabilize cell membranes.

A non-ionic detergent used to solubilize membrane-bound proteins, to precipitate cholesterol, and to permeabilize cell membranes.

A non-ionic detergent used to solubilize membrane-bound proteins, to precipitate cholesterol, and to permeabilize cell membranes.

A non-ionic detergent used to solubilize membrane-bound proteins, to precipitate cholesterol, and to permeabilize cell membranes.

A cardenolide and aglycone constituent of digitoxin that elicits cardiac contraction and cardiotonic effects by inhibiting the Na+/K+ ATPase inhibits protein synthesis and has been examined for use as an antitumor compound.

A cardenolide and aglycone constituent of digitoxin that elicits cardiac contraction and cardiotonic effects by inhibiting the Na+/K+ ATPase inhibits protein synthesis and has been examined for use as an antitumor compound.

A cardenolide and aglycone constituent of digitoxin that elicits cardiac contraction and cardiotonic effects by inhibiting the Na+/K+ ATPase inhibits protein synthesis and has been examined for use as an antitumor compound.

A cardenolide and aglycone constituent of digitoxin that elicits cardiac contraction and cardiotonic effects by inhibiting the Na+/K+ ATPase inhibits protein synthesis and has been examined for use as an antitumor compound.

Dihomo-&gamma-linolenic acid (DGLA) is a metabolite produced by chain elongation of the essential fatty acid &gamma-linolenic acid. Methyl DGLA is an esterified version of the free acid which is less water soluble, but more ammenable for the

Dihomo-&gamma-linolenic acid (DGLA) is a metabolite produced by chain elongation of the essential fatty acid &gamma-linolenic acid. Methyl DGLA is an esterified version of the free acid which is less water soluble, but more ammenable for the