Biologically Active Small Molecules

An analog of curcumin obtained by methylation of both free phenolic groups in the parent compound 30-fold increase in potency was observed in the growth suppression of HCT116 tumor cells following this modification.

An analog of curcumin obtained by methylation of both free phenolic groups in the parent compound 30-fold increase in potency was observed in the growth suppression of HCT116 tumor cells following this modification.

An analog of curcumin obtained by methylation of both free phenolic groups in the parent compound 30-fold increase in potency was observed in the growth suppression of HCT116 tumor cells following this modification.

A planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis 250 &microg/ml stimulates JAK/STAT signaling and induces the expression of interferon-&alpha stimulated genes in a HepG2 cell line.

A planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis 250 &microg/ml stimulates JAK/STAT signaling and induces the expression of interferon-&alpha stimulated genes in a HepG2 cell line.

A planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis 250 &microg/ml stimulates JAK/STAT signaling and induces the expression of interferon-&alpha stimulated genes in a HepG2 cell line.

A planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis 250 &microg/ml stimulates JAK/STAT signaling and induces the expression of interferon-&alpha stimulated genes in a HepG2 cell line.

A cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes also potentiates the insulinotropic potential of glyburide and GLP-1.

A cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes also potentiates the insulinotropic potential of glyburide and GLP-1.

A cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes also potentiates the insulinotropic potential of glyburide and GLP-1.

A cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes also potentiates the insulinotropic potential of glyburide and GLP-1.

A lipophilic electrophile that has profound effects on oxidative and immunological pathways activates the transcription factor Nrf2, resulting in heme oxygenase-1 expression and increased glutathione levels suppresses the expression of