Biologically Active Small Molecules

A long-chain acylcarnitine with both intracellular and extracellular roles transported into mitochondria to deliver palmitate for fatty acid oxidation alters calcium mobilization in many cell types also affects endothelial and epithelial tight

An irreversible inhibitor of the H2S synthesizing enzyme cystathionine-&gamma-lyase (CSE) (IC50 value of 55 &microM).

An irreversible inhibitor of the H2S synthesizing enzyme cystathionine-&gamma-lyase (CSE) (IC50 value of 55 &microM).

An irreversible inhibitor of the H2S synthesizing enzyme cystathionine-&gamma-lyase (CSE) (IC50 value of 55 &microM).

An irreversible inhibitor of the H2S synthesizing enzyme cystathionine-&gamma-lyase (CSE) (IC50 value of 55 &microM).

A major metabolite of sulforaphane that has been shown induce ARE-driven gene expression with roughly 8-fold less potency than sulforaphane.

A major metabolite of sulforaphane that has been shown induce ARE-driven gene expression with roughly 8-fold less potency than sulforaphane.

A major metabolite of sulforaphane that has been shown induce ARE-driven gene expression with roughly 8-fold less potency than sulforaphane.

A PDMP mixture containing D-threo (1R,2R) and L-threo (1S,2S) PDMP reduces the synthesis of glucosylceramide increases cellular ceramide, and induces cell cycle arrest.

A PDMP mixture containing D-threo (1R,2R) and L-threo (1S,2S) PDMP reduces the synthesis of glucosylceramide increases cellular ceramide, and induces cell cycle arrest.

A PDMP mixture containing D-threo (1R,2R) and L-threo (1S,2S) PDMP reduces the synthesis of glucosylceramide increases cellular ceramide, and induces cell cycle arrest.

A ceramide analog that inhibits glucosylceramide synthase with an IC₅₀ value between 2 and 20 &microM.