Biologically Active Small Molecules

An anthelmintic antibiotic that at 0.001 &microg/ml is fully effective at inhibiting growth in an H. contortus larval development assay.

A broad spectrum antibiotic that is in the &beta-lactam subclass known as carbapenems effective against many Gram-negative and Gram-positive bacteria and is more effective against P. aeruginosa than other carbapenems not effective against MSRA.

A broad spectrum antibiotic that is in the &beta-lactam subclass known as carbapenems effective against many Gram-negative and Gram-positive bacteria and is more effective against P. aeruginosa than other carbapenems not effective against MSRA.

A broad spectrum antibiotic that is in the &beta-lactam subclass known as carbapenems effective against many Gram-negative and Gram-positive bacteria and is more effective against P. aeruginosa than other carbapenems not effective against MSRA.

A broad spectrum antibiotic that is in the &beta-lactam subclass known as carbapenems effective against many Gram-negative and Gram-positive bacteria and is more effective against P. aeruginosa than other carbapenems not effective against MSRA.

A potent, reversible inhibitor of AMPK (Ki = 109 nM) dose-dependently inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6) downregulates the Akt/mTOR pathway to induce autophagy in U251 human

A potent, reversible inhibitor of AMPK (Ki = 109 nM) dose-dependently inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6) downregulates the Akt/mTOR pathway to induce autophagy in U251 human

A potent, reversible inhibitor of AMPK (Ki = 109 nM) dose-dependently inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6) downregulates the Akt/mTOR pathway to induce autophagy in U251 human

An inhibitor of carbonic anhydrase, inhibiting human isoforms II, V, VI, IX, XII, XIII, and XIV with Ki values between 3.5 and 52 nM less effectively inhibits human carbonic anhydrases I, III, and IV (Ki = 50, 8, and 8.

An inhibitor of carbonic anhydrase, inhibiting human isoforms II, V, VI, IX, XII, XIII, and XIV with Ki values between 3.5 and 52 nM less effectively inhibits human carbonic anhydrases I, III, and IV (Ki = 50, 8, and 8.

An inhibitor of carbonic anhydrase, inhibiting human isoforms II, V, VI, IX, XII, XIII, and XIV with Ki values between 3.5 and 52 nM less effectively inhibits human carbonic anhydrases I, III, and IV (Ki = 50, 8, and 8.

An inhibitor of carbonic anhydrase, inhibiting human isoforms II, V, VI, IX, XII, XIII, and XIV with Ki values between 3.5 and 52 nM less effectively inhibits human carbonic anhydrases I, III, and IV (Ki = 50, 8, and 8.