Biologically Active Small Molecules

A chemoselective probe for detecting sulfenylated proteins in intact cells using click chemistry.

A chemoselective probe for detecting sulfenylated proteins in intact cells using click chemistry.

A cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC₅₀ = 15 &muM) inhibits clathrin-dependent vesicle formation and endocytosis can also augment the release of

A cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC₅₀ = 15 &muM) inhibits clathrin-dependent vesicle formation and endocytosis can also augment the release of

A cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC₅₀ = 15 &muM) inhibits clathrin-dependent vesicle formation and endocytosis can also augment the release of

A cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC₅₀ = 15 &muM) inhibits clathrin-dependent vesicle formation and endocytosis can also augment the release of

A heptadecapeptide that acts as an endogenous opioid receptor agonist (Kis = 0.5-1 nM for &kappa, &micro, and &delta) has been implicated in antinociceptive functions.

A heptadecapeptide that acts as an endogenous opioid receptor agonist (Kis = 0.5-1 nM for &kappa, &micro, and &delta) has been implicated in antinociceptive functions.

A heptadecapeptide that acts as an endogenous opioid receptor agonist (Kis = 0.5-1 nM for &kappa, &micro, and &delta) has been implicated in antinociceptive functions.

A heptadecapeptide that acts as an endogenous opioid receptor agonist (Kis = 0.5-1 nM for &kappa, &micro, and &delta) has been implicated in antinociceptive functions.

A 13-residue opioid peptide that acts as an endogenous &kappa1b-opioid receptor agonist (Ki = 1.1 nM) has been implicated in antinociceptive functions and has also been used to prime cardiogenesis in pluripotent embryonic stem cells.

A 13-residue opioid peptide that acts as an endogenous &kappa1b-opioid receptor agonist (Ki = 1.1 nM) has been implicated in antinociceptive functions and has also been used to prime cardiogenesis in pluripotent embryonic stem cells.