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Add to Cart The item has been addedA2077-25 mgThomas Scientific
EGFR inhibitor used to treat non-small cell lung cancer. It downregulates expression of HER2/EGFR2 and induces apoptosis. (C08-0489-368)
Price: $536.95List Price: $596.62Afatanib is an anticancer chemotherapeutic compound that has been approved to treat advanced lung cancers such as non-small cell lung cancer (NSCLC) and is in clinical trials as a potential treatment for other advanced solid tumors such as breast can -
Add to Cart The item has been addedA2077-100 mgThomas Scientific
EGFR inhibitor used to treat non-small cell lung cancer. It downregulates expression of HER2/EGFR2 and induces apoptosis. (C08-0489-809)
Price: $1,431.91List Price: $1,591.01Afatanib is an anticancer chemotherapeutic compound that has been approved to treat advanced lung cancers such as non-small cell lung cancer (NSCLC) and is in clinical trials as a potential treatment for other advanced solid tumors such as breast can -
Add to Cart The item has been added15363-1A cell permeable, selective inhibitor of the EGFR kinase (IC<sub>50</sub>s = 21, 63, and 4 nM for EGFR and the L858R and L861Q EGFR mutants, respectively). -
Add to Cart The item has been added15363-25A cell permeable, selective inhibitor of the EGFR kinase (IC<sub>50</sub>s = 21, 63, and 4 nM for EGFR and the L858R and L861Q EGFR mutants, respectively). -
Add to Cart The item has been added15363-5A cell permeable, selective inhibitor of the EGFR kinase (IC<sub>50</sub>s = 21, 63, and 4 nM for EGFR and the L858R and L861Q EGFR mutants, respectively). -
Add to Cart The item has been addedC0252-25 mgThomas Scientific
EGFR inhibitor. It induces cell cycle arrest in melanoma cells and inhibits Akt and ERK1/2 in cells lacking ErbB/EGFR receptors. (C08-0488-824)
Price: $248.00List Price: $275.56Canertinib is an irreversible inhibitor of EGFR (HER2/ErbB). This compound is currently in clinical trials as an anticancer chemotherapeutic, displaying activity against a variety of cancers. -
Add to Cart The item has been addedC0252-100 mgThomas Scientific
EGFR inhibitor. It induces cell cycle arrest in melanoma cells and inhibits Akt and ERK1/2 in cells lacking ErbB/EGFR receptors. (C08-0489-467)
Price: $595.33List Price: $661.48Canertinib is an irreversible inhibitor of EGFR (HER2/ErbB). This compound is currently in clinical trials as an anticancer chemotherapeutic, displaying activity against a variety of cancers. -
Add to Cart The item has been addedC0252-250 mgThomas Scientific
EGFR inhibitor. It induces cell cycle arrest in melanoma cells and inhibits Akt and ERK1/2 in cells lacking ErbB/EGFR receptors. (C08-0489-754)
Price: $1,190.82List Price: $1,323.13Canertinib is an irreversible inhibitor of EGFR (HER2/ErbB). This compound is currently in clinical trials as an anticancer chemotherapeutic, displaying activity against a variety of cancers. -
Add to Cart The item has been added17568-1A cell-permeable inhibitor of EGFR and c-ErbB2 (IC<sub>50</sub>s = 20 and 79 nM, respectively) inhibits the proliferation of cancer cells overexpressing either c-ErbB2 or EGFR (IC<sub>50</sub>s = 2.3-2.5 µM). -
Add to Cart The item has been added17568-5A cell-permeable inhibitor of EGFR and c-ErbB2 (IC<sub>50</sub>s = 20 and 79 nM, respectively) inhibits the proliferation of cancer cells overexpressing either c-ErbB2 or EGFR (IC<sub>50</sub>s = 2.3-2.5 µM). -
Add to Cart The item has been added17751-1A selective inhibitor of PDE4 (IC<sub>50</sub> = 72 nM) that antagonizes the Hedgehog signaling pathway activates localized PKA signaling, which, in turn, regulates Gli processing and translocation. -
Add to Cart The item has been added17751-10A selective inhibitor of PDE4 (IC<sub>50</sub> = 72 nM) that antagonizes the Hedgehog signaling pathway activates localized PKA signaling, which, in turn, regulates Gli processing and translocation.
