Biologically Active Small Molecules

A salen-manganese complex with catalase and SOD mimetic activity.

A salen-manganese complex with catalase and SOD mimetic activity.

Aphidicolin is a diterpene antibiotic initially produced by Cephalosporum that exhibits antiviral activities. Aphidicolin inhibits eukaryotic DNA replication by inhibiting DNA polymerase and inducing S phase cell cycle arrest.

Aphidicolin is a diterpene antibiotic initially produced by Cephalosporum that exhibits antiviral activities. Aphidicolin inhibits eukaryotic DNA replication by inhibiting DNA polymerase and inducing S phase cell cycle arrest.

Aphidicolin is a diterpene antibiotic initially produced by Cephalosporum that exhibits antiviral activities. Aphidicolin inhibits eukaryotic DNA replication by inhibiting DNA polymerase and inducing S phase cell cycle arrest.

A naturally-derived flavone with anti-inflammatory, anti-oxidative, and anti-tumor effects induces apoptosis in human cancer cells down-regulates certain genes responsible for cellular oxidative stress, and acts as a selective PPAR&alpha agonist

A naturally-derived flavone with anti-inflammatory, anti-oxidative, and anti-tumor effects induces apoptosis in human cancer cells down-regulates certain genes responsible for cellular oxidative stress, and acts as a selective PPAR&alpha agonist

A naturally-derived flavone with anti-inflammatory, anti-oxidative, and anti-tumor effects induces apoptosis in human cancer cells down-regulates certain genes responsible for cellular oxidative stress, and acts as a selective PPAR&alpha agonist

A naturally-derived flavone with anti-inflammatory, anti-oxidative, and anti-tumor effects induces apoptosis in human cancer cells down-regulates certain genes responsible for cellular oxidative stress, and acts as a selective PPAR&alpha agonist

A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects inhibits PfFabZ and PfFabI (IC₅₀ = 10.7 and 36.

A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects inhibits PfFabZ and PfFabI (IC₅₀ = 10.7 and 36.

A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects inhibits PfFabZ and PfFabI (IC₅₀ = 10.7 and 36.